Bone Abstracts

Within a living organism, the adaptive immune system, e.g. cytotoxic T lymphocytes (CTLs), induce apoptosis in tumor cells, and therefore limit tumor development. Bone marrow is a mysterious hidden place for different tumor cells and the anti-tumor immunity in the bone marrow is important because the specific microenvironment had been considered to contribute to escape of tumor cells from immune attack. However, the practical mechanism of anti-tumor immune elimination by CTLs ...