Bone Abstracts

Our earlier results indicate that prenatal exposure to dexamethasone, synthetic glucocorticoid, may disturb metabolic processes in skeletal system with long-term consequences. Functional foods show a beneficial action that improve the state of health and reduce the risk of disease. The study was performed to determine whether 2-oxoglutaric acid (2-Ox) can abolish the growth inhibiting effect of prenatally administered dexamethasone (DEX) manifested in the growth plate and arti...

Glucocorticoids are the most commonly used drugs in medical therapy, released in stress and necessary for normal development in both humans and animals.The aim of this study was to investigate the effect of prenatally administered dexamethasone (Dex), a synthetic glucocorticoid, on the histomorphometry of the femur in the offsprings of spiny mice, as a precocial species, characterized by high fertility, and the rapid development of the fetal, allowing th...

Acrylamide is a byproduct that forms when certain carbohydrate and aminoacid rich foods are fried, baked, or roasted at high temperatures (>120°C). Our earlier study showed that acrylamide altered the morphology and histology of the small intestinal wall damaging the intestinal barrier and reducing absorption surface. The study was performed to determine whether acrylamide influences gut-bone axis in foetus when administered to guinea pig during the last 35 days of pr...