ba0001oc3.6 | Osteoporosis pathophysiology and genetics | ECTS2013
Moayyeri Alireza
, Hart Deborah
, Erte Idil
, Mangino Massimo
, Hammond Christopher
, Spector Timothy
Background: Recent technological omics advances have empowered us to identify associations between genetic markers and various traits. Knowledge of serum metabolites as intermediary phenotypes can help us achieve a better understanding of the causal pathways from genes to complex diseases like osteoporosis.Methods: In the context of TwinsUK study, serum metabolomic profiles of 6055 participants were assessed using a non-targeted mass spectrom...