ba0005oc1.3 | Clinical trials and osteoporosis treatment | ECTS2016
Roenn Sofie Hertz
, Harsloef Torben
, Pedersen Steen Boenloekke
, Langdahl Bente Lomholt
Background: Clinical studies suggest that vitamin K2 prevents bone loss and may protect against fractures. Vitamin K is a cofactor in the carboxylation of Osteocalcin (OC). Carboxylated OC promotes mineralization of bone. The aim of the study was to investigate the effect of vitamin K2 on osteocalcin, bone mass and -quality.Methods: We conducted a randomized placebo-controlled double-blinded clinical trial, in which 142 postmenopausal osteopenic women we...