ba0001pp75 | Bone development/growth and fracture repair | ECTS2013
Cipitria Amaia
, Reichert Johannes C
, Lange Claudia
, Schell Hanna
, Mehta Manav
, Wagermaier Wolfgang
, Zaslansky Paul
, Fratzl Peter
, Hutmacher Dietmar W
, Duda Georg N
The transplantation of autologous bone graft represents the gold standard treatment for large bone defects, despite the harvesting co-morbidity and limited availability. An alternative scaffold-based approach is presented. Our aim was to investigate to what degree structured scaffolds alone, or in combination with biological stimuli, allow guiding tissue regeneration. Scaffolds consisting of medical-grade polycaprolactone and tricalcium phosphate microparticles, co...