ba0005p35 | Bone biomechanics and quality | ECTS2016
Malgo Frank
, Hamdy Neveen A T
, Pereira Alberto M
, Biermasz Nienke R
, Appelman-Dijkstra Natasha M
Introduction: Acromegaly is a rare disease caused by excess growth hormone (GH) production by an adenoma of the anterior pituitary gland. The skeletal complications of GH and IGF-1 excess include increased bone turnover, increased cortical bone mass and deteriorated microarchitecture of trabecular bone, associated with a high risk of vertebral fractures in the presence of a relatively normal Bone Mineral Density (BMD). There are no data on bone material properties in patients ...