Bone Abstracts

Background: Bone accrual during adolescence is the main contributor to peak bone mass. Bone remodeling is a balance between bone formation and resorption as directed by osteoblast and osteoclast activity, respectively. nitric oxide (NO) is a potent regulator of bone remodeling via mediating effects of cytokines, estrogen and mechanical strain. NO is synthesized from the conversion of L-arginine to L-citrulline by the enzyme nitric oxide synthase (...