ba0003pp144 | Cell biology: osteoblasts and bone formation | ECTS2014
Brion Alice
, Zhang Ganggang
, Piet Marie-Helene
, Moby Vanessa
, Bianchi Arnaud
, Dossot Manuel
, Mainard Didier
, Galois Laurent
, Gillet Pierre
, Rousseau Marthe
Nacre, or mother of pearl, is a promising natural biocompatible biomaterial consisting of aragonite (97%) and of organics (3%) and capable to increase the cell osteogenic activity. It has been established that osteoarthritic osteoblasts present a mineralization defect and, to date, only a few molecules (vitamin D3 and bone morphogenetic protein2) could improve the mineralization potential of this cell type. In this context, we evaluated the impact of nacreous molecules on the ...