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ba0003OP31 | Pre-Clinical | ECTS2014

Increased expression of PTX3 in non-hematopoietic periosteal cells during fracture healing

Kelava Tomislav , Ivcevic Sanja , Katavic Vedran , Kovacic Natasa , Cvija Hrvoje , Petrovic Katerina Zrinski , Kuzmac Sania , Kalajzic Ivo , Bottazzi Barbara , Grcevic Danka

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ba0003pp68 | Bone development/growth and fracture repair | ECTS2014

Increased expression of PTX3 in non-hematopoietic periosteal cells during fracture healing

Kelava Tomislav , Ivcevic Sanja , Katavic Vedran , Kovacic Natasa , Cvija Hrvoje , Petrovic Katerina Zrinski , Kuzmac Sania , Kalajzic Ivo , Bottazzi Barbara , Grcevic Danka

Pentraxin 3 (PTX3) is a highly conserved member of the long pentraxins subfamily produced in response to proinflammatory stimuli. Its biological roles have been associated to infection, female fertility and angiogenesis. We aimed to elucidate the role of PTX3 in the process of fracture healing.WT mice and mice deficient for the PTX3 gene (PTX3-KO) were used, after obtaining the approval from the Ethical committee. Cells from bone marrow and endosteal/per...

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Increased expression of PTX3 in non-hematopoietic periosteal cells during fracture healing

Increased expression of PTX3 in non-hematopoietic periosteal cells during fracture healing

BiosciAbstracts