ba0001pp239 | Cell biology: osteocytes | ECTS2013
Tsourdi Elena
, Salbach-Hirsch Juliane
, Rauner Martina
, Richter Claudia
, Rachner Tilman
, Hofbauer Lorenz
Introduction: Collagen and glycosaminoglycans (GAGs) such as hyaluronan (HA) and chondroitin sulfate (CS) are basic elements of bone structure and collagen-GAG composites are currently developed for a wide range of applications. Here, we report on the molecular and cellular effects of GAGs and their sulfated derivatives on osteocytes, which are fundamental orchestrators of bone remodeling.Materials and methods: The effects of native and sulfate-modified ...