ba0005p236 | Genetics and Epigenetics | ECTS2016
Pepe Jessica
, Bonnet Nicolas
, Herrmann Francois
, Biver Emmanuel
, Rizzoli Rene
, Chevalley Thierry
, Livio Ferrari Serge
Background: Periostin is a matricellular protein involved in bone modeling and remodeling through the modulation of WNT-β catenin signaling in osteoblasts and osteocytes.Aim: To investigate the interaction between polymorphisms of six periostin SNPs and other gene polymorphism involved in periostin expression and activity on periostin serum levels and bone microarchitecture in a cohort of postmenopausal women.Methods: A total ...