ba0005p160 | Cell biology: osteoblasts and bone formation | ECTS2016
Gohin Stephanie
, Pereira Marie
, Belgrave Naomi Weekes
, Lee Ji Sun
, Tompkins Hayley
, Orriss Isabel
, Chenu Chantal
Melatonin is a neuro-hormone released primarily from the pineal gland, which has been shown to have bone anabolic effect, although it is still unclear whether its skeletal action is directly mediated by receptors expressed on bone cells or is indirect. In this study, we examined melatonins effects on bone cellular activities in vitro and tested whether it modifies angiogenesis and blood flow to bone, which are both essential for bone formation.<p class="abst...