ba0001pp400 | Osteoporosis: treatment | ECTS2013
Coudert Amelie
, Lescaille Geraldine
, Baaroun Vanessa
, Azerad Jean
, Cohen-Solal Martine
, Berdal Ariane
, Descroix Vianney
Bisphosphonates (BP) are powerful bone resorption inhibitors. They are used for the symptomatic treatment of malignant osteolytic bone disease (e.g. multiple myeloma and bone metastasis), as well as bone diseases associated with high bone resorption (e.g. postmenopausal osteoporosis, cortisone-induced osteoporosis). However, recent data showed that a rare, but serious, adverse effect of BP therapy is osteonecrosis of the jaw (BRONJ). Given the increasing number of persons rece...