Bone Abstracts

Since its discovery <20 years ago, RNA interference (RNAi) has proven to be a powerful tool for the downregulation of any target gene of choice. This also offers the use of RNAi-inducing small interfering RNAs (siRNAs) in a therapeutic setting, for the knockdown of pathologically overexpressed genes in various pathologies. Beyond siRNAs, this concept has been extended towards microRNAs (miRNAs) and their inhibitors.While the target cell provides the ...