Searchable abstracts of presentations at key conferences on calcified tissues

Bone Abstracts

Published by BioScientifica

Page 8 of about 3069 results

ba0001es2.2 | Approach to the finding of abnormal laboratory results (<emphasis role="italic">Supported by Alexion &amp; IDS</emphasis>) | ECTS2013

Abstract unavailable....
0 shares

ba0001es2.3 | Approach to the finding of abnormal laboratory results (<emphasis role="italic">Supported by Alexion &amp; IDS</emphasis>) | ECTS2013

Low vitamin D

Obermayer-Pietsch Barbara

Supported by Alexion & IDS)-->Low vitamin D serum levels have been associated with a considerable number of diseases and conditions and have attracted significant attention of the scientific community as well as of health authorities all over the world. However, discussions and controversies are ongoing about the reliability, significance and correct ranges of low vitamin D serum levels. A central goa...
0 shares

ba0001oc1.1 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Disease-specific perception of fracture risk and incident fracture rates among postmenopausal women: findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Gregson Celia , Dennison Elaine , Compston Juliet , Adami Silvano , Adachi Jonathan , Anderson Frederick , Boonen Steven , Chapurlat Roland , Diez-Perez Adolfo , Greenspan Susan , Hooven Frederick , Lacroix Andrea , Nieves Jeri , Netelenbos J Coen , Pfeilschifter Johannes , Rossini Maurizio , Roux Christian , Saag Kenneth , Silverman Stuart , Siris Ethel , Watts Nelson , Wyman Allison , Cooper Cyrus

Patients with improved health understanding have greater autonomy over, and motivation towards, health-related lifestyles. We compared self-perceived fracture risk and 3-year incident fracture rates in postmenopausal women for a range of co-morbid diseases using data from the Global Longitudinal study of Osteoporosis in Women (GLOW).GLOW is an international cohort study involving 723 physician practices across 10 countries in Europe, North America, Austr...
0 shares

ba0001oc1.2 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Hip fractures and bone mineral density of the elderly: importance of serum 25-hydroxy vitamin D

Steingrimsdottir Laufey , Halldorsson Thorhallur , Siggeirsdottir Kristin , Cotch Mary Frances , Eiriksdottir Gudny , Sigurdsson Sigurdur , Harris Tamara , Gudnason Vilmundur , Sigurdsson Gunnar

Introduction: Vitamin D is known to be important for bone health. Still, the significance of serum 25-hydroxy vitamin D concentrations (s-25OHD) for hip fracture risk of the elderly is uncertain. Discordant findings may in part be explained by difficulties of RCTs or large cohort studies to reach both the frail and the healthy elderly. The objectives of this study were to determine the risk of hip fractures of the elderly related to s-25OHD, including both the frail and the he...
0 shares

ba0001oc1.3 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Size at birth is not associated with risk of hip fracture. results from two population-based cohorts

Byberg Liisa , Michaelsson Karl , Koupil Ilona

Early life growth has been suggested to influence bone health. However, the relationship with risk of hip fracture in old age has not been thoroughly investigated. We therefore studied the association between birth weight and hip fracture incidence after age 50 among 10 893 men and women (48% women) from the Uppsala Birth Cohort Study (UBCoS, born 1915–1929) and 1334 men from the Uppsala Longitudinal Study of Adult Men (ULSAM, born 1920–1924). Birth weight was collec...
0 shares

ba0001oc1.4 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Intake and serum levels of α-tocopherol in relation to fractures in elderly women and men

Michaelsson Karl , Wolk Alicja , Byberg Liisa , Arnlov Johan , Melhus Hakan

Recent studies indicate a potential importance of the antioxidant α-tocopherol for bone and the development of sarcopenia. No longitudinal clinical fracture studies have been performed. We aimed to determine whether α-tocopherol intake or serum concentrations are associated with fracture risk in older women and men. We used data from two community-based cohorts, the Swedish Mammography Cohort (SMC; 61 433 women) and the Uppsala Longitudinal Study of Adult Men (ULSAM;...
0 shares

ba0001oc1.5 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Heart failure in patients treated with bisphosphonates

Grove Erik , Abrahamsen Bo , Vestergaard Peter

Background: Bisphosphonates are widely used to prevent and treat osteoporosis. Limited evidence suggest that these drugs may reduce mortality, perhaps by protecting against cardiovascular disease. This study investigated the occurrence of heart failure in patients treated with bisphosphonates.Methods: Nationwide retrospective cohort study from Denmark. All users of bisphosphonates and raloxifene (n=4.831) between 1996 and 2006 (n=102.34...
0 shares

ba0001oc1.6 | Osteoporosis epidemiology and long term treatment complications | ECTS2013

Femur geometrical parameters in the pathogenesis of atypical femur fractures

Morin Suzanne N , Godbout Benoit , Wall Michelle , Belzile Etienne L , Michou Laetitia , Ste-Marie Louis-Georges , Karaplis Andrew C , de Guise Jacques A , Brown Jacques P

Background: Atypical femur fractures (AFF) arise in the subtrochanteric and diaphyseal regions. Because of this unique distribution, we hypothesized that patients with AFF demonstrate specific geometrical variations of their femur whereby baseline tensile forces applied to the lateral cortex are higher and might favor the appearance of these rare stress fractures, when exposed to bisphosphonates.Methods: Subjects who sustained AFF, as defined by the ASBM...
0 shares

ba0001oc2.1 | Bone quality and fracture repair - animal models | ECTS2013

Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of duchenne muscular dystrophy

Puolakkainen Tero , Ma Hongqiang , Pasternack Arja , Kainulainen Heikki , Ritvos Olli , Heikinheimo Kristiina , Hulmi Juha , Kiviranta Riku

Patients with Duchenne muscular dystrophy (DMD) carry a mutation in the dystrophin gene that leads to progressive muscle degeneration. In addition, DMD patients develop low bone mass especially in long bones and have high incidence of fractures. The underlying mechanisms for decreased bone mass remain unclear but muscle weakness and increased IL6 levels may play a role. Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and strength...
0 shares

ba0001oc2.2 | Bone quality and fracture repair - animal models | ECTS2013

Intermittent human parathyroid hormone (1–84) treatment improves bone mass and bone defect healing in rats with type 2 diabetes mellitus

Hamann Christine , Picke Ann-Kristin , Rauner Martina , Bernhardt Ricardo , Campbell Graeme , Gluer Claus-Christian , Hofbauer Lorenz C

The pathogenesis of skeletal fragility in diabetes mellitus is poorly defined and efficient therapies are limited. Zucker diabetic fatty (ZDF) rats with type 2 diabetes mellitus display low bone mass and delayed bone defect healing. We tested whether intermittent treatment with human parathyroid hormone 1–84 (PTH) increases bone mass and bone defect regeneration in diabetic rats.A subcritical gap defect was created at the femur of 10 weeks old diabe...
0 shares

Published by BioScientifica

Bone Abstracts
ISSN 2052-1219 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more