Bone Abstracts

Objective: To study association of VDR gene Fok1 polymorphism locus on bone mass accrual in adolescent girls.Methods: An intervention trial was carried out in 102 girls aged 8–16 years (Pune, India). All girls received 500 mg elemental calcium (daily) and 30 000 IU of vitamin D3 quarterly for 1 year. Outcome variables were measured at baseline and end of the year. Serum levels of ionised calcium (iCa), inorganic phosphorous, parathyroid hor...

Objective: Type 1 diabetes (T1D) in one of the commonest chronic childhood disorders; poor muscle function and sarcopenia has been reported among T1D in adults. Reports on the impairment of muscle function are scarce in children. Our objective was to assess muscle mass and function in children with diabetes and study association of muscle mass and function with control of blood glucose (as measured by HbA1C) and disease duration.Methodology: This was a c...

Objective: Using DXA, we have previously reported that children with type 1 diabetes (T1D) had short and thin bones (Bone, 2015). Calcium supplementation promotes bone mass accrual with sustained benefit observed using milk/milk-based calcium but not calcium salts. To investigate effect of 1-year supplementation with milk vs pharmacological calcium salt on bone mineral density (BMD) and geometryin Indian underprivileged children with T1D. Both groups received vitamin D supplem...