Bone Abstracts

Two kinds of apatite powder were prepared separately from bovine bones originated from different geographical and ecological areas with different climates, in order to characterize and compare their components, hardness and structures by burning them and heat treating the bone ashes at 850 °C in an air furnace. The black ashes were converted to white and yellow–white powders. X-ray diffraction (XRD) analysis indicate that the white powder was carbonate–hydr...

Roundabout receptors are crucial regulators of vessels and axons growth during development. A comparative transcriptomic study between the MDA-MB-231 breast cancer cell line and its osteotropic subpopulation, MDA-B02 cells, has shown an overexpression of ROBO4 receptor. Interestingly, a high ROBO4 expression in primary tumour from patients with breast cancer correlates with poor prognosis and increased risk of bone metastasis relapse. Inoculation of ROBO4 depleted cells in the...