Bone Abstracts

Objectives: Chronic non-bacterial osteomyelitis (CNO) is a heterogenic group of immune-mediated inflammatory bone diseases with unclear pathogenesis. Only a few genes associated with this condition have identified. The aim of the study was to evaluate the spectrum of mutations in genes associated with primary immunodeficiency syndromes (PIDs) and autoinflammatory diseases (AIDs) in the cohort of patients with early-onset CNO from North Caucasus (Dagestan and Chechnya) and asse...

Purpose: To explore the features of bone metabolism and create a system of medical correction of violations in patients with Ehlers-Danlos syndrome.Materials and methods: Based on the analysis of the survey results of 12 patients with different types of EDS aged 3 to 10 years (males - 8 patients, female - 4 patients) who were treated in Institute of Orthopedics and Traumatology,National Academy of Medical Sciences, Kiev, Ukraine from 2005 to 2015 years. ...

Introduction: The effectiveness of intravenous pamidronate was assessed independently and in combination with corrective osteotomy surgery for lower extremity deformities in children with osteogenesis imperfecta.Methods: Orthopaedic treatment was conducted in 21 patients with OI (type I–ten patients, type III–11 patients), including 13 males and eight females with mean age 9.4±0.6. All patients received calcium supplements and active forms...