Bone Abstracts

Rationale: Trabecular Bone Score (TBS) is a texture-based tool analyzing DXA images in order to assess bone microarchitecture in the lumbar region. In pediatric population, definition of normative values has remained elusive due to the disparities of results in normal population, probably link to uncontrolled factors which impact bone microarchitecture and the nonlinear behavior of bone growth. Our objective was to evaluate TBS in healthy Mexican children and adolescents using...

Young transsexuals at a minimum age of 12 years are treated with GnRH-analogues (GnRHa) to suspend pubertal development until the addition of hormones of the desired sex is started at a minimum age of 16 years. The effect of this treatment on adult bone mineral density (BMD) is still unknown. We aimed to assess BMD at the age of 22, as this is near its peak in healthy individuals.In this prospective observational study 19 female to male (FtM) and 16 male...

Background: Three-dimensional scaffolds for the tissue regeneration are also crucial materials for bone formation. In particular, the scaffolds must provide the space for the cell migration and new bone formation. Collagen is one of the useful scaffolds to reach these performance, however, it is not always a desired biodegradability. Recently, we succeeded in developing low adhesive scaffold type I collagen (LASCol) (patent pending) which has the ability to form fibrils. In th...

Background: WHO recommends diagnostic criteria of osteoporosis can be based on double energy absorption of x-ray bone densitometry (DXA), but the DXA method has some limitations such as relatively higher cost, relatively longer detection time, inconvenience in equipment transportation and so on. Quantitative Ultrasound (QUS) method has the potential to diagnose osteoporosis and it is convenient to carry around and low-cost. Asian osteoporosis self-assessment tool (OSTA) is an ...

Background: Postmenopausal women are at high risk for osteoporosis, and early adoption of osteoporosis-preventative behaviours, such as physical activity and dietary calcium intake, can help mitigate this risk. Behavioural studies have shown that knowledge and health beliefs are key factors associated with adoption of healthy behaviours. There are few such studies regarding osteoporosis in South America. Our aim was to conduct an exploratory study evaluating osteoporosis-relat...

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Introduction: Osteoporosis is the musculoskeletal disease, the most common complication of liver osteodystrophy. Combined with vitamin D deficiency, they expose the patient to increased risk of fracture, increased morbidity and impaired quality of life.The objective of the study is to evaluate the vitamin D status and the prevalence of densitometric osteoporosis in 100 patients followed for chronic liver diseases.Materials and meth...

Background: ‘Play Plans’ are now being routinely used at the NHS England Sheffield Severe, Complex and Atypical Osteogenesis Imperfecta Service (SCAOI) as an intervention designed to enhance early development. These plans are MDT formulated and encompass carefully targeted activities designed to meet the child’s needs at their exact stages of development across five domains; Cognition, Social & Emotional Development, Motor, Adaptive Skills and Communication ...

Osteogeneses Imperfecta (OI) is a skeletal dysplasia which affects collagen biosynthesis. As with other chronic conditions it is recognised that the heterogeneity of perspectives between parents and health care professionals (HCP) can alter the course of a child’s health outcomes irrespective of the child’s disease. This qualitative study was employed to explore a mother’s lived experience of having a child with OI.Objectives: To gain impr...