Bone Abstracts

The authors present own group of 4213 patients treated with bisphosphonates (BFs) and development of atypical fractures (AF) after 2 years follow up. At the beginning 2147 patients were treated with alendronate and 2066 with ibandronate. Totally 15 fractures were found in the alendronate group (two in adult patients with osteogenesis imperfecta) and 14 in the ibandronate group (one in adult patients with osteogenesis imperfecta). All radiographic examinations were subjected to...

Melorheostosis together with osteopoikilosis, ostepathia striata and Buschke–Ollendorfov’s syndrom belongs to mesodermal sclerotic dysplasia. Melorheostosis is a very rare disease with an incidence of 1:1 000 000, which was firstly described by French neurologist Léri in 1922. Hyperdense bands prominent upon the outer cortex niveau are visible on X-rays of long bones diaphysis reminding flowing wax of a candle. This disease is connected with contractures of soft...

Aim: Evaluate the differences with densitometry after 2-year treatment in patients with breast cancer and LBMD.Materials and methods: A 2 year duration longitudinal study was done in patients diagnosed with breast cancer sent to the Rheumatology Osteoporosis Unit in Hospital d’Ontinyent, who required supplements of calcium and vitamin D+bisphosphonates after a risk fracture study. Socio-demographic data, breast tumor characteristics, risk f...

Contemporary elemental imaging techniques are greatly contributing into the bone research. Synchrotron radiation induced confocal micro x-ray fluorescence technique (SR-μXRF) was employed for the analysis, being the most powerful and sufficient tool in detection and characterization of trace element distributions in bone tissue. Manganese (Mn), as a potential contributor into the mechanisms of calcium incorporation into bone tissue is in the spotlight of research. Further...