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ba0001pp217 | Cell biology: osteoclasts and bone resorption | ECTS2013

Collagen-induced arthritis reduces osteoclast differentiation potential and activity and impairs reactivity to neurotransmitter stimuli in an experimental arthritis rat model

Muschter Dominique , Schafer Nicole , Rainer H Straub , Grifka Joachim , Grassel Susanne

Osteoclast (OC)-mediated bone destruction is a key feature of rheumatoid arthritis (RA). In RA synovial tissue a reduced density of catecholaminergic nerve fibres has been observed. Studies on sweat gland innervation proved that catecholaminergic fibres have the ability to undergo a phenotypic transition to cholinergic nerves. The sympathetic neurotransmitters norepinephrine (NE), acetylcholine (ACh), and vasoactive intestinal peptide (VIP) affect osteoclastogenesis oppositely...

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ba0003pp377 | Other diseases of bone and mineral metabolism | ECTS2014

Fine-needle aspiration with PTH measurement facilitates minimally invasive parathyroidectomy – report of two cases

Grigorie Daniel , Ioachim Dumitru , Stanescu Bogdan , Sucaliuc Alina , Caragheorgheopol Andra

Objective: Minimally invasive parathyroidectomy (MIP) has become a frequently used strategy but it requires a precise preoperative localization and the use of intraoperative PTH to fulfill its benefits. The current localization techniques (ultrasonography, MIBI scan) have shortcomings and intraoperative PTH is not available in our country.Case presentation: We report the cases of two patients, females (63 and 55 years old), with clinical and biochemical ...

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Bone Abstracts

Collagen-induced arthritis reduces osteoclast differentiation potential and activity and impairs reactivity to neurotransmitter stimuli in an experimental arthritis rat model

Fine-needle aspiration with PTH measurement facilitates minimally invasive parathyroidectomy – report of two cases

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