Bone Abstracts

The femoral neck fractures (FNF) are one of the most common non-traumatic fractures in elderly people. Frequently the patients with fractures of this localization need surgical treatment and long-term rehabilitation. It’s widely known that FNF in patients with rheumatoid arthritis (RA) occur more often than in the population.Background: To determine the frequency of FNF in patients with RA and to characterize the patients with RA and with FNF at the...

There is discussed an interrelation of BMD, progressing of erosive and destructive changes in hands and feet with development of vertebral deformations in rheumatoid arthritis (RA).The aim: To receive data on bone mineral density (BMD), erosive and destructive changes in hands and feet and vertebral deformations in patients with RA.Materials/methods: In this research, it was included 106 women, with RA, age 23–69 years. In all...

Background: The activity of rheumatoid arthritis (RA) is the one of the significant reasons of the increase of bone resorption and decrease of bone mineral density (BMD). The control of activity of inflammatory process with biologics (including rituximab – anti-CD20 antibodies) can be considered as possibility of decrease in bone resorption and BMD stabilization.Objectives: To access the dynamics of BMD after 24 months of treatment with rituximab in...

Background: It is known that one of the features of rheumatoid arthritis (RA) is a generalized bone loss, therefore important tasks for the physician are timely evaluating of the risk of fractures and approving osteoporosis treatment in patients with RA.Objectives: Through the Programme of the Russian Association of Rheumatology for the diagnosis, prevention and treatment osteoporosis (OP) in patients with RA we evaluated the 10 year probability of major...

Age is one of the most important factors that influence bone condition. At the age of 40–45 years for women (F) and 50 years for men (M) processes of bone formation and resorption are balanced, then bone resorption predominates.We examined 103 M (20–78 years) and 360 F (20–87 years), residing in the Republic of Karelia. Densitometry was performed for all patients to assess age-related changes in bone mineral density (BMD) at the lumbar spi...

Children with chronic gastroduodenitis (CGD) have decreased absorption of nutrients, minerals particularly, which can influence on bone strength and linear growth.Objectives: We evaluated bone mineral density (BMD) in children with CGD and compared with healthy individuals.Methods: BMD was measured in 97 children aged 5–13 years by lumbar spine DXA (DPX MD+, Lunar) with pediatric reference database. BMD was evaluated according...

Introduction: Cartilage intermediate layer protein (CILP) is a promising marker of osteoarthritis (OA). CILP is an extracellular matrix glycoprotein, which is produced by cartilage chondrocytes. Still, there are data that CILP could be found also in other tissues. We aimed to investigate the expression level of CILP mRNA in the synovial membrane and evaluated the associations of CILP expression with traits of radiographic knee OA (rKOA) and features of histol...

Aim: The aim of the research is to define the bone mineral density in patients, with Parkinson’s disease.Methods: We examined 12 women with Parkinson’s disease and 12 healthy women of appropriate age (average age: −63.6±6.25 vs 62.2±6.83 years, P=0.5). The duration of Parkinson’s disease was at list 5 years. All patients reseived levodopa.Results: BMD of women with Parkinson’s disease wa...

Objectives: Spinal muscular atrophy (SMA) results in varying degrees of hypotonic immobility. Prior reports demonstrate an increased risk of fracture and a trend toward low bone mineral density (BMD) in this population. We aim to further characterize bone health in paediatric SMA patients by reporting the prevalence of fractures and low BMD (z-score≤−2.0) by SMA subtype, BMD of the lateral distal femur (LDF; an important fracture location in non-ambulatory...

Objectives: The purpose of our study was to evaluate the bone mineral accrual in children with osteogenesis imperfecta (OI) treated by pamidronate (PAM).Methods: In retrospective study 43 children with different types of OI were included: 17 boys (39.5%) and 26 girls (60.5%). According to clinical OI, patients were: OI I type -13 (30.2%), OI III type – 24 (55.9%) OI IV type – 4 (9.3%), OI V type 1 (2.3%) and Bruck syndrome 1 (2.3%). The standar...