Bone Abstracts

The objective of this investigation was to compare bone mineral density (BMD) attained from dual-energy X-ray DXA with speed of sound (SOS) data attained from a Beam-Med Omnisense multisite quantitative ultrasound (mQUS) in a large sample of randomly-selected community-based individuals from the Canadian Multicentre Osteoporosis Study (CaMOS). A total of 1177 men and 2949 women were assessed with mQUS at the distal radius, tibia, and phalanx sites as part of the Canadian Multi...

This investigation sought to assess the relationship between physical activity (PA) and estimated bone stiffness as assessed by multisite quantitative ultrasound (mQUS) in a large cohort. A total of 1177 men and 2949 women were assessed with mQUS (Beam-Med Omnisense quantitative ultrasound; Isreal) at the distal radius, tibia, and phalanx sites as part of the Canadian Multicentre Osteoporosis Study (clinical sites included Saskatoon, Calgary, Hamilton, Quebec City, Halifax and...

This investigation sought to assess the relationship between vitamin D and calcium intake and estimated bone stiffness as assessed by multisite quantitative ultrasound (mQUS) in a large cohort. A total of 1177 men and 2949 women were assessed with mQUS (Beam-Med Omnisense quantitative ultrasound; Isreal) at the distal radius, tibia, and phalanx sites as part of the Canadian Multicentre Osteoporosis Study (clinical sites included Saskatoon, Calgary, Hamilton, Quebec City, Halif...

Turner syndrome (TS) is known to be associated with increased risk of osteoporosis and fracture. Childhood treatment with GH has been considered standard of care for treatment of growth failure in TS, while the influence of GH on bone health has been poorly understood. The purpose of this study is to assess the influence of GH on bone microarchitecture on a cohort of TS subjects.TS subjects aged 16–45 were included. Bone mineral density (BMD) was as...

Prof. David Little received his Medical Degree from the University of Sydney where he is Conjoint Professor of Paediatrics and Child Health, specialising in Orthopaedic Surgery. Prof. D Little is Head of Orthopaedic Research and Biotechnology at The Children’s Hospital at Westmead, part of the Sydney Children’s Hospital Network. He has broad clinical interests in Children’s Orthopaedi...

Abstract unavailable....

Tibial dysplasia, which leads to fracture and pseudarthrosis, occurs in around 4% of children with NF1, and also in children with no underlying disorder. Pseudarthrosis of the fibular may or may not be present, or as an isolated entity, as can pseudarthrosis in the forearm (rare). Other bone problems faced by individuals with NF1 are scoliosis (20%), pectus excavatum/carinatum (12%), and sphenoid wing dysplasia (7%). Dural ectasia and plexiform neurofibromas can also affect th...

Abstract unavailable....

Background: Children with inflammatory bowel disease (IBD) have reduced bone mineral density (BMD). The aim of this study was to investigate whether changes in patient’s cellular immune response correlate with reductions in BMD.Method: Children undergoing lower gastrointestinal endoscopy disease were approached with an aim of recruiting 15 patients newly diagnosed with Crohn’s Disease (CD) and 15 healthy controls. Lymphocytes were isolated from...

This paper reviews clinical reports of vitamin D deficiency rickets in neonates from 1930 onwards. In 24 reports there was good evidence of maternal deficiency. In some the diagnosis of the rickets led to the identification of symptomatic osteomalacia in the mothers; several had been severe and longstanding. Of the 15 mothers who had assays for serum 25-hydroxyvitamin D (25OHD) 13 had values <25 nmol/l (10 ng/ml) and 10 had values <12.5 nmol/l (5 ng/ml).<p class="a...