Bone Abstracts

This study was performed to characterize the effects of calcium phosphate coated and hydroxyapatite coated zirconia compared to smooth surfaced zirconia with bone marrow-derived osteoblast culture.Bone marrow-derived osteoblasts were cultured on i) smooth zirconia, ii) zirconia coated with calcium phosphate (CaP), and iii) zirconia coated with hydroxyapatite (HA). The tetrazolium-based colorimetric assay (MTT test) was used for examining the attachment o...

The objective of our study is to determine whether GNAS expression correlates with pathognomonic signs by analyzing mutations, methylation status, and G-protein α subunit (Gsα) expression of GNAS (guanine nucleotide binding protein/α stimulating) gene in Ewing Sarcoma (ES).Formalin-fixed paraffin-embedded (FFPE) tissue samples from 77 patients with primary ES were obtained in Korea, Argentina, and Brazil, and w...

Background: Aromatase inhibitors (AIs) increase the risk of fracture in patients with breast cancer. Therefore, we aimed to evaluate the long-term effects of AIs on bone health in postmenopausal women with primary breast cancer.Patients and methods: We performed a retrospective longitudinal observational study in patients with breast cancer who were treated by AIs for ≧3 years (baseline T-score >–2.5). Patients with previous anti-osteoporosis...