Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp7 | Arthritis and other joint diseases: translational and clinical | ECTS2014

Do osteophytes protect femoral neck against fracture in osteoarthritis?

Rabelo Gustavo Davi , Roux Jean Paul , Portero-Muzy Nathalie , Boutroy Stephanie , Chapurlat Roland , Chavassieux Pascale

Beside the bone mass, structural changes are important determinants of the bone strength. Patients with osteoarthritis (OA) seem protected against femoral neck (FN) fracture. When compared to osteoporosis, FN in OA are characterized by a higher bone mass and a better trabecular microarchitecture (Blain et al., 2008, Boutroy et al., 2011). The presence of microcracks is one of the determinants of the bone strength. The aim of this study was to evaluate the mic...

ba0005p18 | Biochemical testing | ECTS2016

Atorvastatin effects on a glucocorticoid-induced osteoporosis animal model

Pacheco-Pantoja Elda , Rojano-Carrillo Brahim , Mateo-Moguel Pablo , Dominguez-Angulo Cindy , Aguilar-Aleman Gustavo , Lopez-Rivas Victor

Osteoporosis is a chronic disease with a high prevalence in older adults. There is evidence that statins have some beneficial effects on bone metabolism. Although the trial reports are ambiguous, it is now accepted that statins block the osteoclast differentiation inhibiting to some extent bone resorption. Our aim was to evaluate the effects of a statin in an animal model, which was induced to osteoporosis by glucocorticoids and then treated with atorvastatin. The experimental...