Bone Abstracts

Objective: To investigate the characteristics and related factors of bone mineral density (BMD) in men of different ages with type 2 diabetes.

Methods: Four hundred and forty four male patients diagnosed with type 2 diabetes and 208 healthy men were involved from 2013 to 2014. The BMD of all men including lumbar spine (L1–L4), femoral neck, trochanter, and total hip were detected using dual-energy X-ray absorptiometry produced by the US company. We grouped the patient with T2DM by every 10 years old and compare their BMD. And we also grouped the healthy men and patients by every 5 years old. Then we compared their differences. The correlation analysis of BMI, duration of diabetes, creatinine, serum calcium, phosphorus, the level of lipid and BMD was performed.

Results: i) The BMD of neck and Ward’s triangle are different among different age with T2DM (P<0.05). ii) The BMD of Ward’s triangle between the T2DM one and the healthy one are different in 40–44 (0.737±0.255 vs 0.582±0.162) (P<0.05), while there is no difference in 45–59. iii) The BMD of L1 with T2DM was positively correlated with BMI, Cr and Ca (r=0.258, 0.132, 0.108). The BMD of L2, L3 was positively correlated with BMI, Cr (L2 r=0.189, 0.094 vs L3 r=0.123,0.105). The BMD of L4 was positively correlated with BMI (r=0.115). The BMD of torch, neck, Ward’s triangle, Htot were positively correlated with BMI, TC, Ca and P, while they were negatively correlated with age and duration (P<0.05).

Conclusion: It shows that the BMD between T2DM and healthy people is different when matched with age. There are many factors for men with T2DM to have influence on BMD in different parts., especially BMI, age and duration. We should pay more attention to the men with type 2 diabetes who are more than 50 years old in case of osteoporosis.