Bone Abstracts

Introduction: Osteoporosis (OP) as cardiovascular diseases are causes of morbidity and mortality. Several publications have shown a relationship between the OP and coronary heart disease (MC). Their coexistence was considered separate conditions related to age, and was mainly attributed to aging and common risk factors including diabetes, dyslipidemia, and smoking.

Study Objective: To assess the prevalence of BMD bone loss in patients treated for coronary artery disease compared to a control population.

Materials and methods: This is a prospective, case-control, bi-centric longitudinal bearing CHD patients followed for CHU Ibn Rushd Cardiology Service of Casablanca between 2014 and 2015. The exclusion criteria were all patients with pathology weakening the bone. Patients were divided into two groups, one group bearing coronary artery disease and the second control group with normal coronary angiography. All patients underwent a complete physical examination, a complete calcium and phosphate, metabolic, and bone densitometry.

Results: The study was conducted in 46 patients, including 22 men and 24 women. The mean age was 65.7±6.5 years. For the record, they found 34% had diabetes type II, 60% on insulin, 21% had dyslipidemia, 80% on statins, 32% had hypertension and 17% were chronic tobacco. Of the 46 patients, 10 (21.7%) had osteoporosis, 19 (41.3%) had osteopenia, and 17 (37%) had normal bone mineral density. The prevalence of osteoporosis and osteopenia was significantly greater in group I than in group II.

Discussion: Szulc et al. found an association between BMD, bone turnover markers and risk of myocardial infarction and stroke in 744 men over 50 years. Even since 1990, the Framingham study showed an inverse relationship between cortical thickness of the metacarpals and the risk of occurrence of coronary events, and after adjustment for cardiovascular risk cofactors.

In this sense, numerous publications describe a link between bone fragility and cardiovascular disease, but never establish proof of a cause-effect relationship.

Conclusion: Several studies have shown the association between osteoporosis and cardiovascular disease. The mechanisms are multiple and still imperfectly understood. It seems legitimate to propose a DXA sick “vascular” and a cardiac evaluation with osteoporotic subjects.

Conclusion: In light of these results, we stress the need for health education and the establishment of a preventative oral health in osteoporotic postmenopausal women.