ECTS2016 Poster Presentations Osteoporosis: evaluation and imaging (39 abstracts)
Prevalence of vertebral fractures kept constant in postmenopausal women in Beijing, China: peking vertebral fracture (PK-VF) study, 2007–2012
Ruizhi Jiajue 1 , Yan Jiang 1 , Qiuping Wang 2 , Wenbo Wang 3 , Yu Pei 4 , Xiran Wang 5 , Wei Huang 6 , Xin Zheng 7 , Zhiwei Ning 8 , Ou Wang 1 , Mei Li 1 , Xiaoping Xing 1 , Wei Yu 9 , Ling Xu 10 & Weibo Xia 1
1Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China; 2Department of Endocrinology, Beijing Liangxiang Hospital, Beijing, China; 3Department Endocrinology, Peking University Shougang Hospital, Beijing, China; 4Department of Geriatric Endocrinology, Chinese PLA General Hospital, Beijing, China; 5Department of Cadre Unit, General Hospital of the Second Artillery Force, Beijing, China; 6Department of Endocrinology Beijing Haidian Hospital, Beijing, China; 7Department of Endocrinology, China Rehabilitation Research Center, Beijing, China; 8Department of Endocrinology, Beijing Chaoyang Hospital, Beijing, China; 9Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China; 10Department of Gynaecology and Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China.
Purpose: PK-VF study, being conducted in 2007–2008 and 2012–2013, was aimed to investigate the prevalence and 5-year incidence of vertebral fractures (VFs) in postmenopausal women aged 50 years or older in Beijing, China.
Methods: In the 2007–2008 survey, we randomly selected a community-based population of 1825 postmenopausal women, of whom 952 women also participated in the 2012–2013 survey. Adopting the same sampling strategies as 2007–2008 survey, in the 2012–2013 survey, we additionally selected 1101 postmenopausal women, and a total of 2053 subjects were finally included. VFs were confirmed by the lateral radiographs of the thoracolumbar spine (T4-L5), being evaluated by two experienced radiologists. To investigate the secular trend of VFs, we standardized the prevalence of VFs in the 2012–2013 survey to the age composition of 2007–2008 population. Pearson χ2 test was conducted to compare the incidence of VFs between subjects with and without VFs in 2007–2008.
Results: The actual prevalence of VFs was 24.8% (95% CI, 22.8–26.8%) in 2007–2008, and 24.1% (95% CI, 22.3–26.0%) in 2012–2013. The age-standardized prevalence of VFs in 2012–2013 was 23.3% (95% CI, 21.5–25.1%) and was insignificantly decreased 0.94-fold (95% CI, 0.84–1.05), comparing to 2007–2008. The 5-year incidence of VFs during 2007–2012 period was 5.3% (95% CI, 3.8–6.7%). Comparing to subjects without VFs in 2007–2008, subjects with VFs had a 2.605-fold (95% CI, 1.460–4.650) higher risk getting a new VF in the following 5 years.
Conclusions: The rates of VFs kept constant in postmenopausal women in Beijing, China, during 2007–2012. History of previous VF was a potential risk factor of incident VF.
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