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Bone Abstracts

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43rd Annual European Calcified Tissue Society Congress

Rome, Italy
14 May 2016 - 17 May 2016

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Poster Presentations

Bone Marrow

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Bone development/growth and fracture repair
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Bone Matrix

ba0005p78 | Bone Marrow | ECTS2016

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ba0005p79 | Bone Marrow | ECTS2016

Bone marrow adipose tissue and bone turnover in postmenopausal osteoporotic women and the effects of raloxifene

Beekman Kerensa , den Heijer Martin , Maas Mario , Bisschop Peter , Bravenboer Nathalie

Background: In postmenopausal osteoporosis, a loss of bone volume due to increased bone turnover is accompanied by a higher volume of bone marrow adipose tissue (BMAT). If this static relationship is based on a functional relationship, BMAT is a potential target for treating osteoporosis. While it is known that estrogen can reduce BMAT, it is still unknown whether raloxifene – a selective estrogen receptor modulator – can also reduce BMAT.Objec...
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ba0005p80 | Bone Marrow | ECTS2016

Multi-potency and immunosuppressive activity of mesenchymal stromal cells derived from human induced pluripotent stem cells

Roux Clemence , Saviane Gaelle , Pini Jonathan , Dihib Gihen , Nourhene Belhaid , Wakkach Abdel , Blin-Wakkach Claudine , Rouleau Matthieu

Tissue healing/reconstruction as well as exacerbated inflammatory diseases may benefit from stem cell based therapies. Ex vivo isolated tissue mesenchymal stromal cells (MSCs) displaying multi-potent activity and immune-regulatory functions were long ago proposed as therapeutic cells and already tested in many clinical assays. Nevertheless, their use may be restricted because of the few number that can be recovered from adult tissues, their limited in vitro e...
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ba0005p81 | Bone Marrow | ECTS2016

Increased bone marrow adiposity in energy deficit context: tip of the iceberg?

Ghali Olfa , Leterme Damien , Coutel Xavier , Resonet Anne , Marchandise Pierre , Miellot Flore , Penel Guillaume , Hardouin Pierre , Chauveau Christophe

Context: An increase in bone marrow adiposity (BMA) is usually described in anorexia nervosa (AN) patients and in calorie restriction models. This induced BMA could be involved in the development of the osteoporosis often described in AN. However, BMA increase is not always observed and could be depending on the severity of the deficit.We previously developed the separation-based anorexia mouse model (SBA)1 (Ethical approval CEEA #022012). SBA...
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Bone Abstracts
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