Bone Abstracts

Contents

• ECTS 2016
• • Management of osteoporosis with focus on osteoporosis in men, pregnancy and patients treated with glucocorticoids
  • • Pregnancy associated Osteoporosis: Pathophysiology and management

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    • Male Osteoporosis: Secondary causes and evidence based treatment

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    • Vertebroplasty and kyphoplasty; evidence based treatment of painful vertebral fractures?

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    • Longterm management of Osteoporosis treatment: Treatment failure, treatment breaks

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    • Evidence versus emminence:Treatment of glucocorticoid induced osteoporosis in premenopausal women

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  • Management of rare bone diseases
  • • Osteogenesis imperfecta in the adult: does age make any difference to the need of care?

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    • Fibrous dysplasia in the adult

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    • Bone marrow oedema syndrome

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    • Emerging treatments of rare bone diseases - relevance for the adult patient?

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    • Paget's disease of bone

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• Allied Health Professionals Session
• • Speakers
  • • Bone Structure and Function: Organization [amp] composition of bone, bone modelling and remodelling, bone cells

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    • Pathophysiology of Bone Loss: Growth and loss, changes in microarchitecture, molecular mechanism, hormonal regulation, nutritional influence

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    • Biomechanical modelling of bone: predicting bone strength and fracture risk using engineering approaches

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    • Osteoporosis treatments: past, present and future

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  • Abstract Presentations
  • • Age-dependent changes in the bone marrow microenvironment

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    • To measure or not to measure? Vitamin D and parathyroid hormone in patients with clinical risk factors for osteoporosis

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    • Treat-to-target in osteoporosis. Mith or reality? Results of a spanish Delphi study

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• Muscle and Bone Session
• • Muscle & Bone
  • • The bone and muscle connection - perspectives of a bone scientist

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    • Signalling pathways in muscle and bone - perspectives of a muscle scientist

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    • Mechnotransduction in muscle and bone

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    • Principles of locomotion and adaptation throughout the lifespan

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    • Sarcopenia and frailty -- the clinical picture

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    • Imaging bone and muscle - established and new techniques

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    • Translational studies on muscle hypertrophy and function

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    • Sarcopenia medications in clinical studies

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    • Exercise regimens and musculoskeletal response

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    • Sarcopenia and nutrition

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• Main Symposium
• • What is new – the year in review
  • • What is new: clinical bone research highlights

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    • What is new: bone basic science highlights

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  • Insights from Outside: New Frontiers in Therapy
  • • Targeted gene therapy

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    • Therapeutic potential of RNA interference

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    • Genome editing

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  • Microbiome and musculoskeletal health
  • • Gut microbiota and bone metabolism

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    • Treatment perspectives for gut microbiota

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  • East Meets West
  • • Local and systemic drug delivery systems for bone tissue regeneration

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    • Relevance of vitamin D to pathogenesis and treatment of osteoporosis

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    • Development of osteoconductive and osteoinductive bone healing materials

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  • Molecular Clocks
  • • Circadian clocks, ageing and age-related diseases

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    • Good times, bad times: (patho)physiology of diurnal rhythms

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  • Joint ECTS/ASBMR Symposium: Bone Therapeutics Update
  • • Treatment of X-linked hypophosphatemia with anti-FGF-23

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    • PTH and PTHrP treatment for osteoporosis

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• Workshops – Clinical & Pre Clinical
• • Preclinical imaging beyond bone mass
  • • LivE imaging for in vivo cellular profiling

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    • Intravital microscopy of bone and bone marrow

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    • Acoustic assessment of bone properties beyond bone mineral

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  • Stem cells – can we go from bench to patient?
  • • Skeletal stem cells

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    • The challenge of translating stem cell therapies to the clinic: what you need to show regulators

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    • Stem cell treatments for osteopetrosis

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  • MicroRNA and bone
  • • microRNA and WNT signaling

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    • miRNA in diabetic bone disease

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    • Therapeutic implications

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  • Osteoporosis: Treat-to-target
  • • Defining a goal for the treatment of osteoporosis

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    • Which target to choose: a biomechanics perspective

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    • Uncoupling of resorption and formation; the tool to reach the treatment goal

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  • Chronic kidney disease and bone
  • • Bone fragility in chronic kidney disease

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    • Bone and mineral metabolism in end-stage kidney disease

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    • Is PTH the good target to reduce fractures?

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  • Update on Parathyroid Disease
  • • The genetic bases of hypocalcaemia

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    • Clinical consequences of long-term hypocalcaemia

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    • Management of hypoparathyroidism

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• Hot Topic Oral Communications
• • (1)
  • • Storage disease and neurological phenotype in autosomal dominant osteopetrosis type 2 (ADO2). A preclinical study

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    • Mice lacking estrogen receptor [alpha] in hypothalamic POMC neurons display enhanced estrogenic response on cortical bone mass

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    • Deletion of protease-activated receptor-2 improves bone and muscle pathology in dystrophin-deficient (mdx) mice

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    • Vitamin D supplementation in pregnancy leads to greater bone mass in UK infants born during winter months: the MAVIDOS multicentre, randomised, double-blind, placebo-controlled trial

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    • Superior Gains in Bone Mineral Density (BMD) and Estimated Strength at the Hip for Romosozumab Compared With Teriparatide (TPTD) in Women With Postmenopausal Osteoporosis Transitioning From Bisphosphonate Therapy: Results of the Phase 3 Open-label STRUCTURE Study

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    • Effect of KRN23, a fully human anti-FGF23 monoclonal antibody, on rickets in children with X-linked hypophosphatemia (XLH): 40-week interim results from a randomized, open-label Phase 2 study

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• Cancer and Bone Oral Communications
• • Oral Communications
  • • Secreted YB-1 (Y-box binding protein 1) as a biomarker of bone disease progression in patients with breast cancer and bone metastases

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    • Bone and metabolic parameters are associated with overall survival in patients with bone metastases from adenocarcinoma lung cancer: the POUMOS study

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    • Blocking IL-1R signalling inhibits breast cancer growth and bone metastases by altering the tumour microenvironment

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    • Prostate cancer microRNAs in extracellular vesicles stimulate osteoclastogenesis

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    • Integrin α5 is an independent prognosis factor and a potential therapeutic target for breast cancer bone metastasis

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    • Cancer cell homing to the bone marrow is modulated by the mesenchymal stromal cell

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    • Peripheral tumour re-growth following combination therapy - role of the bone microenvironment

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    • Inhibition of BMP signalling reduces bone destruction and impacts niche maintenance in a mouse model of multiple myeloma

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    • Blockade of C5aR impairs tumor-induced osteoclastogenesis preventing bone metastasis colonization in lung cancer

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    • Osteoblasts inhibit the immune response against cancer

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    • Visualizing the tumor immunity in living bone marrow by intravital 2-photon imaging

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    • Anti-sclerostin treatment prevents multiple myeloma bone disease and reduces tumour burden

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    • Targeting skeletal metastatic breast cancer with bisphosphonic matrix metalloproteinase-2 inhibitors

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    • Muscle dysfunction in immune competent mice with osteolytic breast cancer in bone is associated with skeletal muscle oxidation of RyR1

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    • Bisphosphonates prevent osteolysis and muscle weakness in aromatase inhibitor-treated mice with breast cancer bone metastases

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    • In vitro mechanotransduction of osteosarcoma cells

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    • 3D tissue engineered constructs for modeling tumor-induced bone disease

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    • New models of breast and lung cancer bone metastases for preclinical efficacy testing

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  • Oral Poster Talks
  • • Osteoblastic and osteolytic bone metastases induce divergent angiogenic responses

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    • Roundabout receptors: new actors in bone metastatic niche formation

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    • Cripto/Grp78 drive the metastatic phenotype in human osteotropic prostate cancer

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    • p62-ZZ domain signaling inhibition prevents MM cell-induced epigenetic repression at the Runx2 promoter and rescues osteoblast differentiation

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    • Antagonizing Mir-218 prevents breast cancer-induced osteolytic disease

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    • Mesenchymal stromal cells promote osteosarcoma stemness and migratory potential via IL-6 secretion

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    • Abstract unavailable

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    • Lysyl oxidase promotes survival and outgrowth of colon cancer cells in the bone marrow, enabling bone metastasis formation

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• New Investigator Oral Communications
• • Abstract Presentations
  • • Rictor plays a critical role in bone mass and strength with the involvement of Mtorc2 pathway in osteoblasts

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    • Circulating microRNAs in postmenopausal women with osteoporosis and vertebral fractures

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    • Tumor necrosis factor superfamily members in bone loss in men with end-stage chronic obstructive lung disease

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    • The correlation between number and population of bone marrow endothelial progenitor cells with bone mass and bone metabolism in the elderly

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    • Altered bone metabolism after high fat diet and exercise: role of Wnt signaling and insulin resistance

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    • Multi-potency and immunosuppressive activity of mesenchymal stromal cells derived from human induced pluripotent stem cells

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    • Exposure to chronic stress induces bone loss via glucocorticoid signalling in osteoblasts

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    • Bone marrow adipose tissue and bone turnover in postmenopausal osteoporotic women and the effects of raloxifene

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    • Inflammatory conditions induces a new subset of osteoclasts that prime TNF[alpha]-producing CD4+ T cells

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• Oral Communications
• • Clinical trials and osteoporosis treatment
  • • Efficacy of odanacatib in postmenopausal women with osteoporosis: subgroup analyses of data from the phase 3 long-term odanacatib fracture trial (LOFT)

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    • Acute effects of calcium supplements on blood pressure: results of a randomised cross-over trial

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    • Treatment with vitamin MK-7 prevents deterioration of trabecular bone

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    • Relationship between total hip (TH) BMD T-score and incidence of nonvertebral fracture (NVFX) with up to 10 years of Denosumab (Dmab) treatment

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    • Secular trends in prescription incidence of different anti-osteoporotic drugs in the UK population aged 50 years or above from 1990 till 2012

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    • Standard QCT shows substantial underestimation of treatment effects on bone mineral density: impact of spatial resolution

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  • Bone mass and bone strength Wnt signalling
  • • Targeted deletion of Wnt1 in mesenchymal cells results in decreased bone mass and spontaneous fractures

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    • Deletion of Dickkopf-1 in osteoblasts or osteocytes increases bone volume in female mice

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    • Life-course GWAS approach for total body BMD unveils 16 new BMD loci with some exerting age-specific effects

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    • Up-regulation of Wnt antagonists contributes to the attenuated response of bone formation to repeat doses of sclerostin antibody in a mouse model

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    • Is circulating sclerostin an endocrine modulator of bone mass?

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    • N-cadherin maintains osteoprogenitor number and restrains Wnt signaling in osteoblasts

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  • Clinical trials, FGF-23 and focal osteoporosis
  • • Effect of odanacatib on bone density and estimated bone strength in postmenopausal women: a CT-based sub-study of the phase 3 long-term odanacatib fracture trial (LOFT)

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    • Effects of Denosumab (Dmab) on bone matrix mineralization: results from the phase 3 FREEDOM trial

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    • Vitamin D supplementation reduces pregnancy chances: a randomized, placebo-controlled trial

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    • The response of fibroblast growth factor-23 to teriparatide in postmenopausal osteoporosis

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    • Low serum iron is associated with high serum FGF23 in elderly men: the Swedish MrOS study

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    • Focal osteoporosis associated with hip fracture involves both trabecular and cortical bone; a 3D cortical bone mapping study of cases and controls using clinical CT

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  • Catabolism and metabolism
  • • A small molecule inhibitor of TRAF6 dependent signaling reduces osteoclastogenesis and prevents ovariectomy induced bone loss

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    • Inhibition of Sphingosine 1 Phosphate produced by Osteoclasts reduces chondrocyte catabolism and prevents osteoarthritis in mice

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    • Connecting the dots between bone and energy metabolism: the role of Lipocalin 2

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    • Osteocyte-specific ablation of Ppar[gamma] improves energy metabolism and prevents fat accumulation but not bone loss in response to a high fat diet

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    • Effects of glucagon-like peptide-1 receptor agonists on bone blow flow and architecture in diabetic mice

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    • The myokine Irisin improves bone quality and strength

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  • Risk factors for fracture, Pagets disease of bone and musle and bone
  • • High serum miRNA 550a-5p levels are risk factors for incident fractures in older postmenopausal women with type 2 diabetes

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    • Impaired bone material properties increase the risk of all fractures and severity of vertebral fractures in osteoporosis: an impact microindentation study

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    • Osteoprotegerin autoantibodies are independently associated with low hip bone mineral density and increased fracture risk in patients with ankylosing spondylitis

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    • Fine mapping of the chromosome 1p13 locus for susceptibility to Paget's disease of bone

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    • The relationship between muscle strength and bone outcomes in ageing UK men

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    • The metabolic alterations behind bone fragility in Duchenne muscular dystrophy

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  • Development and differentiation (or Aging)
  • • Analyses of structural and functional impact of three FGFR3 mutations localized at position K650 leading to both mild and lethal dwarfism

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    • Bone with uncleavable type I collagen C-propeptide has abnormal development of multiple bone cell populations and increased bone mineral density with age

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    • The critical biomechanical role of Lipocalin 2 in the crosstalk between endothelium and osteoblasts in unloading conditions.

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    • Extranuclear effects of estrogen on cortical bone in males is dependent on estrogen receptor A activation function-1

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    • Absence of cyclophilin A impairs endochondral bone formation by altering intracellular signaling pathways required for osteoblast maturation

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    • Loss of the longevity gene SirT1 dysregulates chondrocytes and leads to an arthritic phenotype in vivo, via impaired autophagy

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• Oral Posters
• • Clinical
  • • Effects of calcifediol versus cholecalciferol on 25(OH)D3 serum levels, appendicular muscle strength, and physical performance in post-menopausal women

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    • Abstract unavailable

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    • Vitamin D supplementation for 12 months in older people prevents bone loss and suppresses parathyroid hormone levels

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    • Identification of a novel locus on 2q13 of large effect size which predisposes to clinical vertebral fractures independently of BMD: the GEFOS consortium

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    • Predicting hip fracture type of elderly Asian patients with low-energy fall by volumetric BMD and femoral morphology from QCT

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    • Gender-different relationship between body composition and incident fracture risk in Koreans: a community-dwelling prospective cohort study

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    • Can bone turnover markers help to define the duration of bisphosphonate drug holidays?

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    • Two-fold regional variation in initiation of anti-osteoporosis medication after hip fracture in the UK

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    • Short-term smoking cessation improved bone formation in healthy male smokers

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  • Pre-Clinical
  • • Pathophysiological implication of Autotaxin on osteoclast function

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    • Phosphorylation of S122 in ER[alpha] is important for the skeletal response to estrogen treatment

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    • Loss of androgen receptor suppresses chondrogenic proliferation during endochondral ossification in mice

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    • The CAM assay for human bone regeneration evaluation: the potential of Laponite clay gel for growth factor delivery ex vivo

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    • Loss of type I collagen telopeptide lysyl hydroxylation causes musculoskeletal abnormalities in a zebrafish model of Bruck syndrome

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    • Two different domains of fibronectin stimulate osteoblast differentiation by activating distinct integrins

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    • Bcl-2-associated athanogene-1 (BAG-1) regulates chondrocyte and osteoblast development

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    • Transgene expression by Dmp1 promoter fragments occurs in various organs

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    • Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production

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  • Clinical (1)
  • • Profiles of 25 hydroxyvitamin D and its metabolites 24, 25-dihydroxyvitamin D and 1, 25-dihydroxyvitamin D in vitamin D3 supplementation studies

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    • Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz therapy among HIV-infected individuals

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    • Impact of 3-year vitamin D and calcium supplementation on mineral and organic matrix formation of trabecular bone in postmenopausal osteoporosis

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    • Trabecular (spine) bone density increases significantly in the first six months after weaning (factors affecting bone formation after breastfeeding pilot study (FABB-Pilot))

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    • FGF23 and SCL are expressed in carotid plaques and the association between their circulating fractions and fractures differs in relation to comorbidity in elderly individuals

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    • Secondary bone size deficit in patients with Ehlers-Danlos syndrome

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    • Validation of a novel scoring system, the radiographic global impression of change (RGI-C) scale, for assessing skeletal manifestations of hypophosphatasia in infants and children

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    • Atypical femur fractures (AFF): a case-control study

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    • Acute kidney injury after a single intravenous zoledronic acid administration in patients with osteoporosis

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  • Pre-Clinical (1)
  • • Neuropetide Y Y1 receptor deletion impairs matrix demineralization and resorption

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    • Hif1alpha leads to chondrodysplasia in MMP-deficient mice

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    • Bone loss in KLHL3 knock-in mice characterized by a pseudohypoaldosteronism type II-like phenotype is mediated by renal PTH resistance

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    • Early deletion of menin in the osteoblast lineage results in decreased bone mass in adult mice

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    • Pharmacological activation of the non-canonical TGF-[beta] signaling is a novel strategy to enhance bone formation

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    • Long-term high-dose resveratrol supplementation reduces bone mass and strength in rats

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    • RCOR2 is a novel regulator of osteoblast differentiation

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    • Identification and functional validation of microRNA expression in human bone tissue

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    • MicroRNA-125b in bone matrix plays a crucial role in osteoblast-osteoclast communication

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• Poster Presentations
• • Arthritis and other joint diseases: translational and clinical
  • • The role of fibroblast growth factor in the destruction in rheumatoid arthritis

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    • Does adiponectin in serum or synovial fluid predict arthroscopy assessed cartilage damage severity in patients with symptomatic knee osteoarthritis?

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    • The influence of secondary hyperparathyroidism -at the time of index operation- on the later development of (septic or aseptic) loosening of implants in female patients with knee osteoarthritis who undergo total knee arthroplasty

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    • Immune system and bone cells in early rheumatoid arthritis

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    • The effects of hydroxychloroquine on bone turnover

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    • Effects of 17[beta]-estradiol and mechanical overloading on osteoarthritis of rat temporomandibular joint

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    • Effect of estrogen deficiency on loaded and non-loaded area of temporomandibular or knee Joint

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    • A clinical study to examine thresholds of joint space width and joint space area for identification of knee osteoarthritis

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    • Apolipoprotein E aggravates inflammation and bone destruction in murine antigen - induced arthritis

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    • Identifying cell populations coupling inflammation to osteoresorption in arthritis

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    • Chemotactic signals mediating osteoclast progenitor migration in collagen induced arthritis

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  • Biochemical testing
  • • Improvement on growth of osteoporotic bone tissue around screw and fixation strength of screw induced by stress force from the expanding pedicle screw: dynamic microstructural, histological and biomechanical studies in osteoporotic sheep lumbar vertebrae

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    • Evaluation of serum levels progranulin and bone morphogenetic protein-4 in patients with osteoarthritis

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    • Hematologic indices and osteoarthritis

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    • Serum osteopontin and bone sialoprotein levels in patients with tendinopathy

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    • Evaluation of hematologic parameters in patients with tendinopathy

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    • Effects of subcutaneous administration of caffeine on bone markers in rats

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    • Atorvastatin effects on a glucocorticoid-induced osteoporosis animal model

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    • A novel highly specific ELISA allows the measurement of human periostin in plasma and serum

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    • Frozen for 7 years: How long can bones be stored prior to biomechanical testing?

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    • Profiles of 25 hydroxyvitamin D and its metabolites 24, 25-dihydroxyvitamin D and 1, 25-dihydroxyvitamin D in vitamin D3 supplementation studies

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  • Bone biomechanics and quality
  • • Finite element analyses predict the mechanical impact of cam-FAI surgery on ovine femurs

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    • Impact of visceral adiposity on trabecular bone score in obese postmenopausal women: A cohort study

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    • Epidemiological and biomechanical influences on the prevalence and progression of periprosthetic osteolisis after total hip replacement: analysis with magnetic resonance imaging

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    • Effect of paracetamol on bone mechanical properties in rats

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    • Doxazosin prevents the development of estrogen deficiency-induced osteoporosis in rats

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    • Relationships between morphometric, densitometric and mechanical properties of tibiotarsal bone in 14-month-old ostriches (Struthio Camelus)

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    • Alendronate therapy improves anterior vertebral microstructure in osteoporotic bone facilitating fracture risk reduction

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    • Modified stable supracondylar corrective osteotomy technique for Genu Valgum

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    • Chemical composition of the trabecular bone with and without osteoarthritis

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    • Site specific bone loss induced by spaceflight in mice: a multiscale evaluation of trabecular and cortical structure and quality

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    • Characterization of bone using ultrasonic waves and structural borne acoustic waves

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    • Assessment of changes in collagen associated with advanced glycation end-products in human bone using vibrational spectroscopy

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    • Abstract unavailable

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    • Bone material properties as measured by Reference Point Indentation are low in subjects with acromegaly

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    • Finite element analysis of osteoporotic lumbar vertebrae L1 under dynamic loading

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    • Elemental composition of compact human bone correlated with the osteocyte network

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    • Arthritis induces early bone structural degradation and mechanical weakness

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    • Depth and location dependence of subchondral trabecular structure across the tibia in human osteoarthritic knee versus normal knee: a micro-CT study

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    • Atypical fractures of femur after longterm bisphosphonates treatment: two years follow up

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    • Investigation of the potential link between mechanosensory proteins PC1/PC2 and craniosynostosis

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    • Sexually dimorphic response on bone development after neonatal thymectomy in rats

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  • Bone development/growth and fracture repair
  • • Serum of patients with active rheumatoid arthritis inhibits differentiation of osteochondrogenic precursor cells

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    • Effect of a mixture of GOS/FOS(R) on calcium (Ca) and phosphorus (P) absorption and bone retention in ovariectomized osteopenic rats fed a low calcium diet

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    • Mast cells regulate inflammation and bone regeneration in fracture healing

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    • Bone regeneration using transcript-activated matrices for sustained messenger RNA delivery

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    • Bone-forming ability of recombinant human bone morphogenetic protein 2 after repeated administration in mice

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    • Biocompatibility of hydroxyapatite derived from whitemouth croaker (Micropogonias furnieri)

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    • The effects of combined teriparatide and denosumab on bone regeneration

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    • Prostaglandin IP agonist promotes osteoblastic differentiation and BMP induced bone formation

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    • Rictor plays a critical role in bone mass and strength with the involvement of mtorc2 pathway in osteoblasts

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    • Effect of intermittent administration of teriparatide (PTH 1-34) on BMP induced bone regeneration in a rat critical-sized femoral defect model

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    • Effect of bioactive glass-ceramic scaffold associated with bone marrow - or adipose-derived mesenchymal stem cells on bone formation under osteoporotic conditions

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    • Role of interleukin-6 in the early and late fracture healing phase

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    • Calcium and vitamin-D supplementation post-trauma improves bone healing and decreases posttraumatic bone resorption in an osteoporotic mouse model

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    • Morphological and densitometric properties of tarsometatarsus in adult male and female emu (Dromaius Novaehollandiae)

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    • Interrelationships between morphometric, densitometric and mechanical properties of femur in ostriches (Struthio Camelus)

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    • Loss of androgen receptor suppresses chondrogenic proliferation during endochondral ossification in mice

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    • Midkine is involved in the pathogenesis of delayed osteoporotic fracture healing after ovariectomy in mice

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    • Role of PHOSPHO1 in chondrocyte matrix vesicle mineralization: an AFM study

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    • Advanced phase gestational jet lag reduces bone mass of adult offspring

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    • Bcl-2-associated athanogene-1 (BAG-1) regulates chondrocyte and osteoblast development

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    • Comparison of bone stiffness during fracture healing in the human distal radius assessed with HR-pQCT using [mu]FEA and FEA based on downscaled images

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    • A novel model for examining chondral bone regenerative potential in adult zebrafish

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    • Effect of postponing puberty and cross-sex hormone therapy on bone turnover markers and BMAD in transgender adolescents

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    • OSTEOGROW: BMP6 device for enhance bone healing

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    • Comparison of osteoconductivity and absorbability of beta-tricalcium phosphate and hydroxyapatite in open wedge high tibial osteotomy

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    • Adiponectin prevents orthodontic tooth movement in rats

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    • The effects of bone wound healing by implanting novel type I collagen scaffolds

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    • Is heparin effective for the controlled delivery of high dose bone morphogeneic protein-2?

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    • Transcriptional analysis of bone healing in mouse: an insight into biological and chronological overlapping genes

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    • Sulfated hyaluronan improves bone defect healing in type 2 diabetic rats by increasing osteoblast function

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    • Combination of novel two-photon photopolymerised scaffolds and bioactive elastin-like-recombinamers induce bone regeneration

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    • In vitro investigation of the effect of Magnetic Resonance guided Focused Ultrasound Surgery on osteosarcoma cell lines

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    • Increased periosteal expansion, Osterix expression and osteogenic potential upon bone injury during perturbed PI3K signaling

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    • Multicentre study reveals poor correlation between in vitro and in vivo assessments of biomaterials for bone-regeneration

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    • The high bone volume phenotype of female nNOS KO mice is not maintained with ageing

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  • Bone Marrow
  • • Abstract unavailable

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    • Bone marrow adipose tissue and bone turnover in postmenopausal osteoporotic women and the effects of raloxifene

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    • Multi-potency and immunosuppressive activity of mesenchymal stromal cells derived from human induced pluripotent stem cells

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    • Increased bone marrow adiposity in energy deficit context: tip of the iceberg?

      ba0005p81
  • Bone Matrix
  • • CRISPR/Cas9-mediated IFITM5 gene editing demonstrates that BRIL (Ser40Leu) substitution suppresses PEDF-mediated activation of PPAR[gamma]

      ba0005p82
    • Cortical bone matrix mineralisation is decreased in TRPV4 deficient male, but not in female mice

      ba0005p83
    • Anabolic parathyroid hormone (PTH) treatment does not alter periosteal bone mineral composition during primary and secondary mineralisation

      ba0005p84
    • MicroRNA-125b in bone matrix plays a crucial role in osteoblast-osteoclast communication

      ba0005p85
  • Calciotropic and phosphotropic hormones and mineral metabolism
  • • Possible paracrine effects of fibroblast growth factor-23 in the regulation of intestinal calcium absorption

      ba0005p86
    • Reciprocal correlation between iron and calcium transport and the hepcidin-enhanced calcium absorption in the duodenum of hemizygous beta-globin knockout thalassemic mice

      ba0005p87
    • Trabecular (Spine) bone density increases significantly in the first 6 months after weaning (Factors Affecting Bone Formation After Breastfeeding Pilot Study (FABB-Pilot))

      ba0005p88
    • Endogenous expression and biological functionality of secreted Klotho in human mesenchymal stem cells

      ba0005p89
    • Bone loss in KLHL3 knock-in mice characterized by a pseudohypoaldosteronism type II-like phenotype is mediated by renal PTH resistance

      ba0005p90
    • PTH and vitamin D in Inuit and non-Inuit in Greenland

      ba0005p91
    • The analysis of missed diagnosis and misdiagnosis of 144 tumor-induced osteomalacia patients

      ba0005p92
    • Constitutively elevated blood serotonin is associated with bone loss and type 2 diabetes in rats

      ba0005p93
    • Automated ELISA for direct measurement of free 25OH vitamin D

      ba0005p94
    • Relationship between risk of preterm birth and vitamin D deficiency

      ba0005p95
    • Clinical characterization and genetic analysis of TRPV4-related skeletal dysplasias in 4 Chinese families

      ba0005p96
    • Vitamin D therapy: the effects of race, skin colour and genotype

      ba0005p97
  • Cancer and bone: basic, translational and clinical
  • • The cigarette smoking condensates effects on microRNA regulation in calcified of bladder carcinogenesis and progression

      ba0005p98
    • DNA-methylation status affects prognostic markers of bone metastasis from breast carcinoma

      ba0005p99
    • The clinicopathological implication of GNAS in ewing sarcoma

      ba0005p100
    • Bisphosphonates and the risk of breast cancer in osteoporotic women: a population-based study

      ba0005p101
    • Inhibition of mTOR signaling by everolimus has concurrent anti-tumor and bone-protective effects in murine osteolytic cancer models

      ba0005p102
    • Conventional and Pagetic Giant Cell Tumor of bone: distinct clinical features are defined by different genetic background and histological appearance

      ba0005p103
    • Long-term effect of aromatase inhibitor on bone mineral density, trabecular bone score, and hip geometry in postmenopausal women with primary breast cancer

      ba0005p104
    • Effects of the female hormone inhibin-A in vivo: potential contribution to the antitumour effect of Zoledronic acid

      ba0005p105
    • The Rho GTPases RhoA and CDC42 mediate apoptosis by a combination of statins and zoledronic acid in human bone-seeking breast cancer cells

      ba0005p106
    • Biological effects of Cabozantinib on bone microenvironment

      ba0005p107
    • Clinical and experimental evidence suggest a protective effect of Paget's disease of bone against skeletal metastasization from solid tumors

      ba0005p108
    • Antiproliferative properties of oleuropein in human osteosarcoma cells

      ba0005p109
    • Role of the receptors FZD8 and RYK in mediating the anti-tumor effects of WNT5A on prostate cancer cells

      ba0005p110
    • Changes in monocyte and NK-like cell subpopulations in the peripheral blood of patients treated with zolendronic acid

      ba0005p111
    • Myeloid-derived suppressor cells (MDSC) mediate the positive feedback loop of prostate tumor-bone interactions

      ba0005p112
    • Dendritic glycopolymers as efficient drug delivery systems for retarded release of bortezomib from calcium phosphate cements

      ba0005p113
    • Increased zinc accumulation in mineralized osteosarcoma tissue

      ba0005p114
    • Polycystin-1 is involved in osteosarcoma pathobiology

      ba0005p115
    • Signaling network of mirnas regulating bone metastasis in lung cancer

      ba0005p116
    • Contribution of multiple myeloma-derived exosomes to bone disease

      ba0005p117
    • Menin is a tumor suppressor in bone -- a novel benign jaw tumor mouse model

      ba0005p118
    • Abstract unavailable

      ba0005p119
    • The role of acidic microenvironment in the context of osteolytic carcinomas

      ba0005p120
    • MCT1 as a novel target for the treatment of osteolytic bone metastases

      ba0005p121
    • Acetate metabolism in Multiple Myeloma identifies ¹¹C-Acetate PET as a novel strategy to image bone disease and response to treatment in preclinical models

      ba0005p122
    • The SRC kinase inhibitor saracatinib limits the development of osteolytic bone disease in multiple myeloma

      ba0005p123
    • Gene expression of P2 receptors in mitotically quiescent, prostate cancer bone metastasis initiating cells

      ba0005p124
    • Host-derived MMP-13 promotes Multiple Myeloma skeletal colonization

      ba0005p125
    • Interactions between cancer and osteocytes in bone

      ba0005p126
    • LIGHT promotes osteolytic bone metastases in NSCLC patients

      ba0005p127
    • The pharmacological profile of a novel highly potent bisphosphonate, OX14 (1-fluoro-2-(imidazo-[1,2 alpha]pyridin-3-yl)ethyl-bisphosphonate), with reduced bone affinity, which is as effective as zoledronate in the treatment of myeloma bone disease in JJN3-NOD/SCID-[gamma] mice

      ba0005p128
    • Vertebral fractures among breast cancer survivors in China

      ba0005p129
    • Uptake of different nitrogen containing bisphosphonate formulations by breast cancer cells

      ba0005p130
    • MicroRNA-30 family regulates bone tropism and osteomimicry in human breast cancer cells

      ba0005p131
    • Osteoblast-derived factors increased metastatic potential in human prostate cancer cells

      ba0005p132
    • Novel evidence that ApoA-1 deficiency facilitates HSC mobilization and differentiation and halts HSC quiescence and self-renewal in mice

      ba0005p133
    • Encapsulation of Gli-inhibitors blocks tumor invasion into the bone

      ba0005p134
  • Cell biology: osteoblasts and bone formation
  • • Up-regulation of inhibitors of DNA binding/differentiation gene during alendronate-induced osteoblast differentiation

      ba0005p135
    • Abstract unavailable

      ba0005p136
    • Delta-like 1/fetal antigen 1 (DLK1/FA1) inhibits BMP2-induced osteoblast differentiation by modulating Nf[kappa]b signaling pathway: a novel mechanism for regulation of bone formation

      ba0005p137
    • Osteoblastogenesis is regulated through the interplay between human arrest defective 1 and runt-related transcription factor 2

      ba0005p138
    • Human bone marrow-derived mesenchymal stem cells response on calcium- and magnesium-ion-implanted resorbable blast media-treated titanium surface

      ba0005p139
    • Matrix metalloproteinases and their inhibitors (TIMPs and RECK): induction of osteoblastic differentiation modulates their protein levels on mineralization onset in human dental pulp stem cells

      ba0005p140
    • Age-dependent changes in the bone marrow microenvironment

      ba0005p141
    • Regulation of genes involved in the integrin signalling pathway induced by titanium with nanotopography

      ba0005p142
    • RUNX2, osterix and the human sclerostin gene: searching molecular and epidemiological interactions

      ba0005p143
    • Primary osteoblast culture from red fox (Vulpes Vulpes)

      ba0005p144
    • Evaluation of release kinetics and mitogenic capacity of collagen barrier membranes supplemented with the secretome of activated platelets

      ba0005p145
    • Pharmacological activation of the non-canonical TGF-β signaling is a novel strategy to enhance bone formation

      ba0005p146
    • Skin-derived IL-17A induces bone loss in the absence of adaptive immunity

      ba0005p147
    • Cationic nacre ethanol soluble matrix has an osteoanabolic effect on human subchondral osteoarthritic osteoblasts and MC3T3-E1 cell line

      ba0005p148
    • Enhancement of bone ultra structure preservation using high-pressure freezing and microwave-assisted fixation

      ba0005p149
    • GPR39 is negatively regulating osteoblast differentiation and bone formation during aging

      ba0005p150
    • Early deletion of menin in the osteoblast lineage results in decreased bone mass in adult mice

      ba0005p151
    • Participation of microRNA-34a/RANKL in the osteogenic potential of the Poly(vinylidene-trifluorethylene)/barium titanate membrane

      ba0005p152
    • RhoA and ROCK regulate spreading of osteoblasts

      ba0005p153
    • Low adhesive scaffold collagen promotes the osteogenic differentiation of rat marrow mesenchymal cells

      ba0005p154
    • L-Carnitine facilitates mitochondrial activity and osteogenic differentiation in human primary osteoblast culture

      ba0005p155
    • The differential effects of zoledronate and etidronate on the in vivo early osseous healing process of an extracted socket and a tibial defect

      ba0005p156
    • Evidence for an osteogenic activity of betaine in human osteoblast in culture

      ba0005p157
    • A single 2-day pulse of activin-A leads to a transient change in gene expression eventually followed by reduction in extracellular matrix mineralization

      ba0005p158
    • Osteogenic superiority of bone marrow-derived osteoblastic cells (ALLOB(R)) over bone marrow-derived mesenchymal stromal cells

      ba0005p159
    • Effect of melatonin on in vitro bone remodelling and blood supply

      ba0005p160
    • Vaspin regulates the osteogenic differentiation of MC3T3-E1 through the PI3K-Akt/miR-34c loop

      ba0005p161
    • RCOR2 is a novel regulator of osteoblast differentiation

      ba0005p162
    • Inhibition of histone demethylase LSD1 suppresses osteoblast differentiation

      ba0005p163
    • Natural uranium triggers autophagy in osteoblasts

      ba0005p164
    • Canine osteoblasts from trabecular, cortical and subchondral bone present differences in alkaline phosphatase activity

      ba0005p165
    • Primary osteoblast culture from domestic dog (Canis lupus familiaris)

      ba0005p166
    • Implication of autophagy in a preclinical mouse model of bone ageing and of osteoporosis

      ba0005p167
    • Two different domains of fibronectin stimulate osteoblast differentiation by activating distinct integrins

      ba0005p168
    • Iron deficiency increases osteoblast function via Wnt5a

      ba0005p169
    • Matrix vesicle-mediated mineralization depends on the balance between annexins and fetuin-A which may be modulated by TNAP and calcium channel inhibitors

      ba0005p170
  • Cell biology: osteoclasts and bone resorption
  • • Notch 2 signaling promotes osteoclast resorption via activation of PYK2

      ba0005p171
    • Rooibos (Aspalathus Linearis) tea extract inhibits osteoclast formation and bone resorption in RAW264.7 murine macrophages, in vitro

      ba0005p172
    • Bone resorption by Tannerella forsythia GroEL

      ba0005p173
    • Abstract unavailable

      ba0005p174
    • A jumonji histone demethylase inhibits osteoclast differentiation through NFATc1 regulation

      ba0005p175
    • Impaired c-kit signaling couples bone resorption to bone formation through wnt10b in kit w-Sh/W-Sh mice

      ba0005p176
    • A novel regulatory factor in osteoclastogenesis DCL-1/CD302: significance of its binding to CCN2/CTGF

      ba0005p177
    • Retrieval of resorptive human osteoclasts from temperature-responsive plastic

      ba0005p178
    • Tensin 3 is a novel partner of dock5 that controls osteoclast podosome organization and activity

      ba0005p179
    • High trabecular bone mass induced by reduced function of osteoclasts in GULP1-deficient mice

      ba0005p180
    • Dual-specificity tyrosine-phosphorylation regulated kinase 2 negatively regulates osteoclast fusion

      ba0005p181
    • Human dendritic cell-derived osteoclasts have the ability for both bone absorption and T cell stimulation

      ba0005p182
    • Life span differs between osteoclasts derived from different bone marrow precursors: a time-lapse microscopy study

      ba0005p183
    • Involvement of integrin beta 2/CD18 in attachment of monocytes to bone

      ba0005p184
    • Characterising the role of the lysosomal membrane proteins MFSD1 and TMEM106b in osteoclasts

      ba0005p185
    • Inflammatory conditions induces a new subset of osteoclasts that prime TNF[alpha]-producing CD4+T cells

      ba0005p186
    • Identification of CX3CR1 as the first known marker of inflammatory osteoclasts

      ba0005p187
    • The Arf and Rho GTPase-activating protein (GAP) ARAP1 regulates osteoclast function

      ba0005p188
    • Pathophysiological implication of Autotaxin on osteoclast function

      ba0005p189
    • Identification and characterisation of vesicles in resorbing osteoclasts using electron tomography

      ba0005p190
    • Homer proteins modulate RANKL-induced NFATc1 signaling in osteoclast differentiation and bone metabolism

      ba0005p191
    • Regulation and function of lentiviral-mediated TCIRG1 expression in osteoclasts from infantile malignant osteopetrosis patients

      ba0005p192
    • C-C chemokine receptor 5, a co-receptor of HIV, -mediated signal is required for geometric architecture and function of osteoclasts, thus for RANKL-induced bone destruction

      ba0005p193
    • Neuropetide Y Y1 receptor deletion impairs matrix demineralization and resorption

      ba0005p194
    • The role of LC3 and autophagy in bone resorption by osteoclasts

      ba0005p195
    • The RECQL4 protein mutated in Rothmund-Thomson syndrome is involved in osteoclast differentiation and function

      ba0005p196
    • Effects of TGF-[beta] inhibition on osteogenesis and osteoclastogenesis by periodontal ligament fibroblasts from patients with fibrodysplasia ossificans progressiva

      ba0005p197
    • Development of a novel sandwich ELISA to quantify human Tartrate Resistant Acid Phosphatase (TRAP) isoforms 5a and 5b protein in one and the same sample

      ba0005p198
    • Identification of G protein-coupled receptor 137B (GPR137b) function in mouse and zebrafish osteoclasts

      ba0005p199
    • RAW264.7 subclones - an in vitro model for osteoclast heterogeneity?

      ba0005p200
    • Galectin-1 is involved in osteoclast biology

      ba0005p201
    • The effect of potassium citrate on human primary osteoclasts in vitro

      ba0005p202
    • The role of light (TNFSF14) on bone remodeling

      ba0005p203
    • Fluoride modulates formation and function of bone marrow macrophage-derived osteoclasts in a strain-specific manner

      ba0005p204
    • Better understanding the potency and cytotoxicity of different bisphosphonates on murine osteoclast formation and activity: implications for its better clinical use in treatment cancers

      ba0005p205
  • Cell biology: Osteocytes, mechanobiology
  • • Post traumatic bone defects treated with induced biomembrane technique in a tertiary care trauma centre - technique, results in 6 patients and a review of literature

      ba0005p206
    • Evidence that osteocyte perilacunar remodelling contributes to polyethylene wear particle induced osteolysis

      ba0005p207
    • Transgene expression by Dmp1 promoter fragments occurs in various organs

      ba0005p208
  • Chondrocytes and cartilage
  • • Crosstalk between FLS and chondrocytes is regulated by HIF-2[alpha]-mediated cytokines in arthritis

      ba0005p209
    • Thyroid hormone locally interacts with the sympathetic nervous system to control bone linar growth

      ba0005p210
    • Benzo(a)pyrene induce the inflammation, nitrosative stress and matrix degradation in articular cartilage

      ba0005p211
    • Histological structure of the mandibular condylar cartilage in rats of various age after 60-day intake of epichlorohydrin

      ba0005p212
    • The vacuolar H+ ATPase V0 subunit D2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation

      ba0005p213
    • Hif1alpha leads to chondrodysplasia in MMP-deficient mice

      ba0005p214
    • Nutritional aspects of skeletal development

      ba0005p215
    • The role of CANT1 in skeletal development with a mouse model of Desbuquois dysplasia type 1

      ba0005p216
    • Effect of combined sex hormone replacement on bone/cartilage turnover in a murine model of osteoarthritis

      ba0005p217
    • Hypoxia inducible factor-1[alpha] directly induces the expression of receptor activator of nuclear factor-[kappa]B ligand in ATDC5 chondrocyte

      ba0005p218
    • Characterization of COMP in zebrafish

      ba0005p219
    • Role of matrilin-3 in the development of osteoarthritis

      ba0005p220
    • miR-214: a novel regulator of chondrogenesis?

      ba0005p221a
    • Vitamin D supplementation for 12 months in older people prevents bone loss and suppresses parathyroid hormone levels

      ba0005p221b
  • Energy metabolism and bone, fat and bone
  • • Changes in circulating osteocalcin concentration in overweight and obese adult women having normal glucose and hemoglobin A1c levels

      ba0005p222
    • Cyclic AMP/protein kinase A signalling downregulates Dlx5 expression via inducing C/Ebp[beta] in 3T3-L1 preadipocytes

      ba0005p223
    • Osteocalcin downregulates pancreatic lipase expression in GPRC6A dependent manner

      ba0005p224
    • Association between bone turnover markers and leptin in girls with adolescent idiopathic scoliosis (AIS)

      ba0005p225
    • Osteocalcin interacts with brain-derived neurotrophic factor, nerve growth factor but not oxytocin in the regulation of bone, energy, brain and reproductive functions

      ba0005p226
    • The role of interleukin-6 and tumor necrosis factor alpha gene in fat and bone communication

      ba0005p227
    • Effects of roux-en-Y gastric bypass surgery on bone quality: a pilot study

      ba0005p228
    • Impaired adipose tissue inflammation results in increased bone mineral density in mice

      ba0005p229
    • The interrelationship of 25-hydroxyvitamin D and osteocalcin on glycolipid metabolism: a cross-sectional study in type 2 diabetics

      ba0005p230
    • Osteocalcin transgenic mice reveal aspects of the bone/glucose axis, as well as powerful suppression of ectopic osteocalcin protein production

      ba0005p231
    • Significant correlation between vasculopathy and bone mineral density in T2DM: new light shed on diabetic osteoporosis

      ba0005p232
  • Genetics and Epigenetics
  • • Differentially methylated regions in gene enhancers of mesenchymal stem cells from osteoporotic patients

      ba0005p233
    • SNP regulation of miRNA expression and its association with osteoporosis

      ba0005p234
    • Periostin serum levels and gene polymorphism are associated with bone microarchitecture

      ba0005p235
    • Interaction between periostin gene (Postn) and other gene polymorphism involved in periostin expression and activity on bone microstructure in humans

      ba0005p236
    • Association among oxidative stress, Wnt signaling and trabecular bone microstructure in osteoporosis and osteoarthritis

      ba0005p237
    • Genetic variants at the Wnt/[beta]-catenin and oestrogen receptor signalling pathways are associated with low bone mineral density in dancers

      ba0005p238
    • Search for BMD-related variants of DKK1 and SOST by resequencing in the BARCOS cohort

      ba0005p239
    • Analysis of the polyalanine repeat polymorphism in the RUNX2 gene in relation to bone mineral density and fracture risk in Maltese postmenopausal women

      ba0005p240
    • Identification of a novel locus on 2q13 of large effect size which predisposes to clinical vertebral fractures independently of BMD: the GEFOS consortium

      ba0005p241
    • A family with Paget disease of bone caused by a novel mutation of hnRNPA2B1 gene

      ba0005p242
    • Geometric morphometrics: a mathematical tool to compare morphological traits based on SOST dysfunction in mice

      ba0005p243
    • NBAS is the gene mutated in two patients affected by Acrofrontofacionasal Dysostosis type 1

      ba0005p244
    • Circulating microRNAs in postmenopausal women with osteoporosis and vertebral fractures

      ba0005p245
    • In a population based association study: IAPP gene variants are not associated with bone phenotypes in elderly women

      ba0005p246
    • Common variants in Rspo 1,2 and 3 do not associate with BMD in stratified subpopulations of the Odense Androgen Study and mutations in these genes are not a common cause of craniotubular hyperostosis

      ba0005p247
    • Identification and functional validation of microRNA expression in human bone tissue

      ba0005p248
    • Identification of epigenomic regulators of osteoblast function

      ba0005p249
    • Advancing maternal age at childbirth is associated with less favourable trabecular bone mineral density and tibial cortical bone geometry in young adult male offspring

      ba0005p250
    • Establishment of an in vivo model to examine the osteoanabolic epigenome

      ba0005p251
    • Mitochondrial DNA point mutation is associated with lower bone turnover markers

      ba0005p252
    • Investigating the osteoanabolic epigenome of aging-related bone loss in humans

      ba0005p253
    • Genetic risk factors for knee osteoarthritis in postmenopausal ukrainian women

      ba0005p254
    • Polymorphism of vitamin D receptor gene, estrogen receptor gene and collagen type I [alpha]1 gene for osteoporosis in Ukrainian women

      ba0005p255
    • OPTN and CCDC3 share a bidirectional promoter region that is regulated by NfkB

      ba0005p256
    • Comparative analysis of human and zebrafish OPTN: molecular and evolutionary perspectives

      ba0005p257
  • Muscle, physical activity and bone
  • • Pamidronate may prevent muscle protein breakdown in burns by indirectly affecting cytokines

      ba0005p258
    • Myths and truths on dietary supplements and nutraceuticals for musculoskeletal health: a scoping review

      ba0005p259
    • Effects of calcifediol versus cholecalciferol on 25(OH)D3 serum levels, appendicular muscle strength, and physical performance in post-menopausal women

      ba0005p260
    • Bone and muscle metabolism in lung transplant recipients

      ba0005p261
    • The role of vitamin D and exercises in correction of age-related skeletal muscle changes in postmenopausal women

      ba0005p262
    • Vitamin D level and hand grip strength as risk factors of actual fall in patients with lumbar spinal stenosis

      ba0005p263
    • UK popular sports and hip differences on bone outcomes in adolescent male athletes: The PRO-BONE study

      ba0005p264
    • Effect of pinealectomy and resistance exercise on rats tibiae morphology, mineral quantification and mechanical parameters

      ba0005p265
    • Inhibition of Cyclooxygenase 2 pathway modulates collagen synthesis of cytokine-stimulated fibroblasts from Ligamentum flavum

      ba0005p266
    • Altered bone metabolism after high fat diet and exercise: role of Wnt signaling and insulin resistance

      ba0005p267
    • Association of frailty with vitamin D in elderly women

      ba0005p268
    • Effects of inorganic phosphate and FGF23 on C2C12 myoblast cells

      ba0005p269
    • A new tapping screw design for anterior cruciate ligament reconstruction

      ba0005p270
    • Skeletal muscle mass is strongly correlated with total Hip BMD in premenopausal women

      ba0005p271
  • Nutrition
  • • Obese young adults exhibit lower total and lower free serum 25-hydroxycholecalciferol in a randomized vitamin D intervention

      ba0005p272
    • Food restriction harms bone properties of prepubertal, but not of young adult or elderly rats

      ba0005p273
    • Caffeine at moderate dose did not affect the skeletal system of rats with streptozotocin-induced metabolic disorders

      ba0005p274
    • Vitamin D from the marine inuit diet and markers of inflammation - a population-based survey in Greenland

      ba0005p275
    • Association between serum 25-hydroxyvitamin D levels and total testosterone levels in Korean adult men

      ba0005p276
    • Association between the sideways fall fractures and body mass index in patients from a public Mexican hospital

      ba0005p277
    • Association of bone mineral density, life style and diet of korean middle aged-men

      ba0005p278
    • Association between lean mass and dietary protein intake in postmenopausal women

      ba0005p279
    • Effects of clinically relevant doses of vitamin A on bone in mice

      ba0005p280
    • Abstract unavailable

      ba0005p281
    • Waist-to-height ratio (WHtR) and coronary artery calcification

      ba0005p282
    • The efficiency of fish scale-derived calcium supplementation on the prevention of bone loss in lactating rats

      ba0005p283
    • Is bone equally responsive to calcium and vitamin D intake from food vs supplements? Use of 41Calcium tracer kinetic model

      ba0005p284
  • Osteoporosis: evaluation and imaging
  • • Postmenopausal osteoporosis: clinical and biological profile, about 70 cases

      ba0005p285
    • Trabecular bone score (TBS) and TBS adjusted FRAX are better indicators for morphometric vertebral fractures than bone mineral density in type 2 diabetic postmenopausal women

      ba0005p286
    • Indentification of the lumbar 1-4 and lumbar 2-4 bone mineral density in women

      ba0005p287
    • Underreporting of vertebral fractures with and without edema on spinal magnetic resonance imaging in adult patients

      ba0005p288
    • Sleep apnea and bone mineral density

      ba0005p289
    • Gender similarities and differences in cross-sectional cortical and trabecular bone of femoral neck in elderly Chinese population

      ba0005p290
    • Prevalence of vertebral fractures kept constant in postmenopausal women in Beijing, China: peking vertebral fracture (PK-VF) study, 2007-2012

      ba0005p291
    • Association between plasma sphingosine 1-phophate levels and incident fractures in postmenopausal women: a 3-year follow-up observation study

      ba0005p292
    • DXA in clinical practice: invest in quality to improve accuracy and clinical relevance

      ba0005p293
    • Establishing an LRP5 mutant zebrafish (D. Rerio) model of bone acquisition

      ba0005p294
    • Risk factors for subsequent vertebral compression fracture following osteoporotic compression fracture

      ba0005p295
    • Predicting hip fracture type of elderly Asian patients with low-energy fall by volumetric BMD and femoral morphology from QCT

      ba0005p296
    • Dexamethasone produces both bone-loss and bone-spare effects in OPG-/- mice

      ba0005p297
    • Bone mass density, yes or no: the effectiveness of BMD test in decreasing the risk for hip fractures in different demographic groups in Israel

      ba0005p298
    • Bone geometry and microarchitecture in patients with anorexia nervosa: a possible role of mechanical loading on cortical bone structure

      ba0005p299
    • Bio-impedance and quantitative ultrasound to measure bone mineral density in post-menopausal women from a rural Mexican community

      ba0005p300
    • Association of serum vitamin D with bone mineral density and breastfeeding in post-menopausal women from a Mexican rural community

      ba0005p301
    • A novel feature selection algorithm based on bone micro architecture analysis to identify osteoarthritis

      ba0005p302
    • Heel quantitative ultrasound parameters, serum 25-hydroxyvitamin D and parathyroid hormone levels of healthy adult women in Greece

      ba0005p303
    • The comparison of bone scan and MRI in osteoporotic compression fractures

      ba0005p304
    • The effect of cemented and uncemented implants on the measurement of proximal femur BMD by DEXA

      ba0005p305
    • To measure or not to measure? Vitamin D and parathyroid hormone in patients with clinical risk factors for osteoporosis

      ba0005p306
    • Bone mineral density and trabecular bone score in ukrainian women with obesity

      ba0005p307
    • The use of calcaneal quantitative ultrasound (QUS) combined with Asian osteoporosis self assessment tools (OSTA) in screening osteoporosis among postmenopausal women

      ba0005p308
    • Tbs and calcaneal ultrasonography in people with down syndrome

      ba0005p309
    • Hormone and hormone responsive stress-related molecules involved in osteoporosis in post-menopausal women

      ba0005p310
    • Increased body weight as a risk factor of intertrochanteric fracture severity in elderly women

      ba0005p311
    • Manganese distribution in bone tissue by SR-[mu]XRF

      ba0005p312
    • Changes of trabecular bone score in Asian females: comparison of 1990s and 2010s

      ba0005p313
    • Inducing osteoporosis in a large animal model: influence of ovariectomy, diet and corticoid therapy

      ba0005p314
    • MRI analysis of the spine in 17 adults with WNT1 osteoporosis

      ba0005p315
    • Correlations between trabecular bone score (TBS), sex, age, height, weight and bone mineral density (BMD): a study of the Korean population

      ba0005p316
    • Cellular and extracellular investigations of healing parameters in a sheep model of osteoporosis

      ba0005p317
    • Circulating microRNA in metabolic bone diseases-osteoporosis

      ba0005p318
    • CORTEX; catching osteoporosis on routine tomography as an added EXtra

      ba0005p319
    • Age and sex features of femoral geometry in patients with hip fractures

      ba0005p320
    • The T-score standard in osteoporotic sheep model: insight into independent reference group

      ba0005p321
    • The essential role of bone biochemistry in the treatment of osteoporosis with rPTH therapy: a large study of over 450 patients

      ba0005p322
    • Trabecular bone score (TBS) and body composition analysis in liver transplantation patients at risk of new-onset diabetes (NODAT)

      ba0005p323
  • Osteoporosis: pathophysiology and epidemiology
  • • Serum 25-hydroxyvitamin D, parathyroid hormone, and bone mineral density in Korean perimenopausal women

      ba0005p324
    • Bone mineral density of lumbar spine and femur in patients with gynaecologic cancer

      ba0005p325
    • Calcium and vitamin D supplementations: 2015 position statement of the Korean society for bone and mineral research

      ba0005p326
    • Gene expression profiling of osteoblastic cells cultured with lithocholic acid or bilirubin. Implications in the pathogenesis of osteoporosis in liver diseases

      ba0005p327
    • Use of proton pump inhibitors and hip re-fractures among Austrian hip fracture patients

      ba0005p328
    • The role of melatonin in regulating autophagy in type 2 diabetic osteoporosis

      ba0005p329
    • Regression analysis between multiple osteoporotic spine fracture and osteoporotic fracture risk factors

      ba0005p330
    • The effects of vitamin D and sarcopenia on bone mineral density in Korean women

      ba0005p331
    • Elevated body iron stores and circulating osteoprotegerin as independent predictors of hip fracture in postmenopausal women admitted for fragility fracture: time for new screening strategies?

      ba0005p332
    • Risk factor profile and bone mass findings

      ba0005p333
    • Incidence of clinical vertebral fractures in north-eastern Germany

      ba0005p334
    • Qulaity of life of patients with osteoporotic vertebral compression fractures

      ba0005p335
    • Epidemiology of community-dwelling elderly vertebral fracture in China southern city: study of osteoporotic fractures (Part I)

      ba0005p336
    • Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz therapy among HIV-infected individuals

      ba0005p337
    • Nonalcoholic fatty liver disease is associated with postmenopausal osteoporosis

      ba0005p338
    • High prevalence of reduced bone mineral density and undertreatment of osteoporosis in patients with systemic sclerosis

      ba0005p339
    • Current trends and future projection of hip fracture in South Korea using nationwide claims data

      ba0005p340
    • Trend of incidence, mortality, and future projection of vertebral fracture in Korea using nationwide claims data

      ba0005p341
    • Short-term smoking cessation improved bone formation in healthy male smokers

      ba0005p342
    • Ultrastructure of biomineral of the ramus of mandible in rats after implantation of manganese enhanced hydroxyapatite implants into tibia

      ba0005p343
    • Ultrastructure of the hipbone biomineral in white rats with defect of the tibia after 60-day administration of sodium benzoate

      ba0005p344
    • The effects of 60-day sodium glutamate intake and exposure to ionizing radiation on ultrastructure of biomineral of the ramus of mandible in rats

      ba0005p345
    • Macroelemental contents of skeletal bones after 60-day exposure to toluene vapors in rats of different ages

      ba0005p346
    • Development of Korean Fracture Risk Score predicting osteoporotic fracture risk: analysis of data from the Korean National Health Insurance Service

      ba0005p347
    • The relationship between osteoporosis and urine ACR in postmenopausal women with type 2 diabetes

      ba0005p348
    • Relationships between the trabecular bone score (TBS) and glucose metabolism indices in healthy postmenopausal women

      ba0005p349
    • Bone mineral density in women with Parkinson's disease

      ba0005p350
    • Gender differences in presentation and outcomes in older hip fracture patients

      ba0005p351
    • Atypical femur fractures (AFF): a case-control study

      ba0005p352
    • Dietary potassium intake is beneficial to bone health in Korean adults with low dietary calcium intake: the Korean National Health and Nutrition Examination Survey (KNHANES) (2008-2011)

      ba0005p353
    • Bone metabolism in patients with anorexia nervosa and amenorrhea

      ba0005p354
    • The correlation between number and population of bone marrow endothelial progenitor cells with bone mass and bone metabolism in the elderly

      ba0005p355
    • The added value to FRAX of gait speed and tests of postural balance

      ba0005p356
    • Older urban Black South African women are increasingly at risk of low bone mass and high bone turnover

      ba0005p357
    • Treatment pattern and its cost of vertebral fracture among elderly patients in Korea

      ba0005p358
    • Glucocorticoid acts differently on vertebral and hip fractures in Korean RA patients using National healthcare claims database

      ba0005p359
    • Warfarin use and changes in bone mineral density in the population-based canadian multicentre osteoporosis study (CaMos)

      ba0005p360
    • The relationship of serum serotonin levels to the rate of bone loss and fractures in men

      ba0005p361
    • Differential influence of social network upon osteoporosis affected by intimacy in Korean elderly women

      ba0005p362
    • Lower FRAX scores but similar femoral neck aBMD in UK dwelling postmenopausal South Asian women as compared with same age Caucasian women

      ba0005p363
    • Peak bone mass and quantitative ultrasound bone properties in young adulthood: a study in the PEAK-25 cohort

      ba0005p364
    • Prevalence and related factors assessment of osteoporotic fracture in rural population: the Korean Genomic Rural Cohort study

      ba0005p365
    • Effect of recent spinal cord injury on the OPG/RANKL system and its relationship with bone loss and antiosteoporotic response to denosumab therapy: preliminary results

      ba0005p366
    • FGF23 and SCL are expressed in carotid plaques and the association between their circulating fractions and fractures differs in relation to comorbidity in elderly individuals

      ba0005p367
    • Gender-different relationship between body composition and incident fracture risk in Koreans: a community-dwelling prospective cohort study

      ba0005p368
    • Osteoporosis-related knowledge and health beliefs among female community leaders in Peru

      ba0005p369
    • Incidence of hip fracture in 2010 in Lithuanian residents over 40 years of age

      ba0005p370
    • Seasonal and environmental effect on the incidence of hip fractures and non hip fractures in Italy

      ba0005p371
    • Sex hormone-binding globulin is associated with markers of vertebral fracture and vertebral fracture risk

      ba0005p372
    • The association between diabetes, trabecular bone score, bone mineral density and vertebral fractures

      ba0005p373
    • Long term follow-up of fracture incidence and fracture prediction from bone mineral density

      ba0005p374
    • Neuropathic pain component in patients with osteoporosis and low back pain

      ba0005p375
    • Tumor necrosis factor superfamily members in bone loss in men with end-stage chronic obstructive lung disease

      ba0005p376
    • Abstract unavailable

      ba0005p377
    • Bone mineral density and associated risk factors: in healthy Indian population

      ba0005p378
  • Osteoporosis: treatment
  • • Clinical features of atypical femur fracture

      ba0005p379
    • Postmenopausal osteoporosis tolerance and efficacy of different therapeutic protocols

      ba0005p380
    • Treatment outcomes during teriparatide use in Greece: country sub-analysis of the Exfos Observational Study

      ba0005p381
    • Effects of single bolus injection of vitamin D on serum FGF23, Sclerostin and DKK1 concentrations in vitamin D-deficient subjects

      ba0005p382
    • A interventional study in a real life setting to assess the clinical efficacy and effect to fracture in the 1 year after the injection of zoledronic acid in osteoporotic patients with long bone or spine, pelvic fractures

      ba0005p383
    • Magnesium together with Calsium and vitamin D improves the bone metabolism in (70y) healtly females

      ba0005p384
    • The effect of teriparatide on fracture healing of vertevral compression fracture in postmenopausal women

      ba0005p385
    • Atypical femoral fractures after long-term bisphosphonates therapy: case report

      ba0005p386
    • Effect of 61-week administration with beta-hydroxy-beta-methylbutyrate on volumetric bone mineral density of lumbar spine in osteoporotic patient

      ba0005p387
    • AMD3100 improves ovariectomy-induced osteoporosis in mice by facilitating mobilization of hematopoietic stem/progenitor cells

      ba0005p388
    • Hypercalcemia after discontinuation of long-term denosumab treatment

      ba0005p389
    • Denosumab therapy results in a high frequency of responders by bone mineral density in both treatment-naive patients and patients switching therapies

      ba0005p390
    • Prevalence of osteoporosis and effectiveness of screening test using ultrasound bone densitometry and education in a community-dwelling population

      ba0005p391
    • The effect of oral dabigatran etexilate on bone density, strength, and microstructure in female and male mice

      ba0005p392
    • Long-term high-dose resveratrol supplementation reduces bone mass and strength in rats

      ba0005p393
    • Inhibitory effects of nanopartical calcium administration on dexamethasone-induced osteoporosis development in axial skeleton of pigs

      ba0005p394
    • Acute kidney injury after a single intravenous zoledronic acid administration in patients with osteoporosis

      ba0005p395
    • Oral health assessment necessary with comprehensive geriatric assessment

      ba0005p396
    • Evaluating dental health risk assessment amongst bisphosphonate users

      ba0005p397
    • Dementia and hip fractures-

      ba0005p398
    • Need for integrated proactive approach for dementia and hip fracture care

      ba0005p399
    • The upper two third of the reference interval of the serum calcium level is required for the optimal increase in lumbar bone mineral density by bisphosphonate and active vitamin D3 analogue for osteoporosis

      ba0005p400
    • Two-fold regional variation in initiation of anti-osteoporosis medication after hip fracture in the UK

      ba0005p401
    • Is recovery of lactation-induced bone loss influenced by immobilization in mice?

      ba0005p402
    • Biochemical monitoring of teriparatide efficacy in a real world setting

      ba0005p403
    • IV. zoledronic acid promotes healing of complicated stress fractures in the foot

      ba0005p404
    • Lithium chloride enhances bone formation and implant osseointegration in osteoporotic condition

      ba0005p405
    • Adherence and persistence to teriparatide treatment in patients attending a specialised Bone Health Service

      ba0005p406
    • Impact of 3-year vitamin D and calcium supplementation on mineral and organic matrix formation of trabecular bone in postmenopausal osteoporosis

      ba0005p407
    • Treat-to-target in osteoporosis. Mith or reality? Results of a Spanish Delphi study

      ba0005p408
    • Atypical femur fracture in an adolescent with X-linked osteoporosis based on PLS3 mutation

      ba0005p409
    • Can bone turnover markers help to define the duration of bisphosphonate drug holidays?

      ba0005p410
    • Establishment of a large sector-spanning fracture liaison service in Germany

      ba0005p411
    • The value of the central vertebral height restoration by kyphoplasty for treatment of biconcave vertebral compression fractures

      ba0005p412
    • Dose postoperative applications of diphosphonate medicine at an early stage have influence on union of fracture?

      ba0005p413
    • Teriparatide reduces the risk of vertebral fractures compared with standard care in patients with severe osteoporosis

      ba0005p414
    • rs72658163, a new heterozygous variant in COL1A2 associated with atypical femoral fracture

      ba0005p415
    • Hydrogen sulfide is a novel regulator of bone formation involved in the bone loss induced by estrogen deficiency

      ba0005p416
    • The fate of injected cement after percutaneous vertebroplasty

      ba0005p417
    • Globular adiponectin reverses trabecular osteopenia in ovariectomized rats

      ba0005p418
  • Other diseases of bone and mineral metabolism
  • • Natural history and prognostic factors of fibrous dysplasia of bone in a modern cohort of 372 patients. The Francedys Study

      ba0005p419
    • Calcification in the vessel wall: impact of vitamin K dependent proteins

      ba0005p420
    • Postmenopausal osteoporosis and periodontal disease about 60 cases

      ba0005p421
    • Bone loss and coronary artery disease, about 46 cases

      ba0005p422
    • Vitamin D status in patients followed for chronic liver diseases

      ba0005p423
    • Bone mineral density changes in kidney transplant recipients

      ba0005p424
    • IL-6/STAT3 pathway is critically involved in vascular calcification via histone modification of the RUNX2 promoter in vascular smooth muscle cells

      ba0005p425
    • Association of circulating dipeptidyl-peptidase 4 levels with osteoporotic fracture in postmenopausal women

      ba0005p426
    • Insulin resistance independently had the negative association with the bone mineral density in Korean young women

      ba0005p427
    • Low bone mass density is associated with tooth loss in postmenopausal women: a nationwide representative study

      ba0005p428
    • Impaired quality of life and muscle function in patients with hypoparathyroidism/hypothyroidism compared with only hypothyroidism and controls

      ba0005p429
    • Type 2 diabetes mellitus increase the risks of incident osteoporotic fractures in Chinese postmenopausal women: a 5-year prospective study

      ba0005p430
    • Bisphosphonate therapy in Langerhans cell histiocytosis: an international retrospective descriptive study

      ba0005p431
    • Differing mechanisms of mineralisation in vascular smooth muscle cells and osteoblasts

      ba0005p432
    • Genetic and clinical characteristics of Chinese pseudohypoparathyroidism patients

      ba0005p433
    • Cyclophilin B deficiency is associated with defective differentiation of bone cell populations and bone hypermineralization

      ba0005p434
    • Association between serum levels of PPAR[gamma] and vertebral fractures in type 2 diabetes mellitus patients

      ba0005p435
    • Determinants of health related quality of life in adults with osteogenesis imperfecta

      ba0005p436
    • Evaluation of targeted next-generation sequencing in diagnosis of Chinese adult-onset idiopathic hypoparathyroidism

      ba0005p437
    • DXA in clinical practice: invest in quality to improve accuracy and clinical relevance

      ba0005p438
    • Quality of life and psysical activicy in patients with non-surgical hypoparathyroidism and pseudohypoparathyroidism

      ba0005p439
    • Mice lacking periostin are resistant to bone microstructural alterations during lactation

      ba0005p440
    • Abstract unavailable

      ba0005p441
    • Investigation of the Paget's disease susceptibility locus on chromosome 15q24 using targeted next generation DNA sequencing approach

      ba0005p442
    • Abstract unavailable

      ba0005p443
    • Deep characterization of a zebrafish model for dominant osteogenesis imperfecta

      ba0005p444
    • Clinical and genetic analysis of multiple endocrine neoplasia type 1-related primary hyperparathyroidism in Chinese: a single-center experience over ten years

      ba0005p445
    • Impacting factors of serum 25-hydroxyvitamin D levels of elderly in community in Shanghai

      ba0005p446
    • The characteristics of bone mineral density in men of different ages with type 2 diabetes

      ba0005p447
    • The characteristics and related factors of vascular calcification(VC) in lower limbs of patients with type 2 diabetes

      ba0005p448
    • MSC injection modulates osteocyte number after high dose single limb irradiation in a murine model

      ba0005p449
    • Cortical density is lower in patients with Graves' disease compared to healthy controls

      ba0005p450
    • Rankl-/- mesenchymal stromal cells have an unexpected osteogenic differentiation defect which is improved by a RANKL-expressing lentiviral vector

      ba0005p451
    • Micro-RNA expression profiling in Paget's disease of bone

      ba0005p452
    • Two novel mutations of RUNX2 gene in two sporadic cleidocranial dysplasia patients

      ba0005p453
    • Bone mineral density and vascular calcification in obesity

      ba0005p454
    • An isoform of fibronectin is responsible for bone loss in hepatic osteodystrophy and its deleterious effects can be prevented by binding the mediating receptor

      ba0005p455
    • Bone mineral density and TBS in patients with mutations of the alkaline phosphatase gene

      ba0005p456
    • Mutant TGF[beta]1 in Camurati-Engelamann disease causes systemic manifestations and reproductive disorders more often than previously thought: report of eight Chinese families

      ba0005p457
    • Colony-stimulating factor 1 receptor a (Csf1ra)-deficient zebrafish as a model of unbalanced bone remodeling

      ba0005p458
    • Clinical, Biochemical and Radiographic Spectrum of X-linked Hypophosphatemia in Adults

      ba0005p459
    • Chloride channel voltage-sensitive 7 (CLCN7) loss-of-function zebrafish as a genetic model of osteoclast-rich osteopetrosis

      ba0005p460
    • The role of bone morphogenetic proteins in muscle regeneration of osteoarthritic patients

      ba0005p461
    • Secondary bone size deficit in patients with Ehlers-Danlos syndrome

      ba0005p462
    • Change in bone mineral density with high-dose prednisone in patients with rheumatoid arthritis

      ba0005p463
    • The course and management of craniofacial fibrous dysplasia: a case series

      ba0005p464
    • Tracking inflammation in mouse model of fibrodysplasia ossificans progressiva prior to the detection of heterotopic ossification as a potential biomarker

      ba0005p465
    • Bone histomorphometric alterations and chronic kidney disease in patients with osteoarthritis and osteoporosis

      ba0005p466
    • Disease activity in patients with rheumatoid arthritis according to vitamin D status

      ba0005p467
    • In vitro model of antioxidant prevention of urolithiasis

      ba0005p468
    • FGF23 and vitamin D metabolism in chronic kidney disease - mineral bone disorder

      ba0005p469
    • Dose response radiation induced bone loss: FDG PET-CT shows a threshold effect in changes in metabolism and density

      ba0005p470
  • Paediatric bone disease
  • • Bone involvement and intervertebral disc calcifications in beta-thalassemic patients: a retrospective study

      ba0005p471
    • Osteogenesis imperfecta: clinical and laboratory aspects, about five cases

      ba0005p472
    • Age of diagnosis of fibrodysplasia ossificans progressiva has a variable onset and a misleading phenotype

      ba0005p473
    • Defining a new severity classification and searching for a pronostic factor in cherubism: NFATc1 localization is the answer

      ba0005p474
    • Validation of a novel scoring system, the radiographic global impression of change (RGI-C) scale, for assessing skeletal manifestations of hypophosphatasia in infants and children

      ba0005p475
    • Childhood fractures in northern Norway: a population-based study, Fit Futures

      ba0005p476
    • Clinical features and targeted gene sequencing analysis of paediatric hypoparathyroidism

      ba0005p477
    • Primary hyperparathyroidism in children and adolescents

      ba0005p478
    • Increased bone resorption markers in young patients with inflammatory bowel disease

      ba0005p479
    • The influence of mobility on bone status in subjects with rett syndrome: a 10-year longitudinal study

      ba0005p480
    • Mutation update and short-term outcome after treatment with active vitamin D₃ in Chinese patients with pseudo-vitamin D-deficiency rickets

      ba0005p481
    • Body composition in children and young patients affected by chronic diseases

      ba0005p482
    • Loss of type I collagen telopeptide lysyl hydroxylation causes musculoskeletal abnormalities in a zebrafish model of Bruck syndrome

      ba0005p483
    • CRTAP variants in early-onset osteoporosis and recurrent fractures

      ba0005p484
  • Preclinical and ex vivo imaging
  • • Sex-related differences of morphological and densitometric properties of mandible in silver foxes (Vulpes vulpes)

      ba0005p485
    • Age-related changes in 3D bone microstructure are more pronounced in the sub-endplate region than in the central region of human vertebral bodies

      ba0005p486
    • The CAM assay for human bone regeneration evaluation: the potential of Laponite clay gel for growth factor delivery ex vivo

      ba0005p487
    • Mandibular bone: an unusual trabecular bone?

      ba0005p488
    • Quantitative assessment of radial bone structural distribution in the proximity of degradable implants by micro-computed tomography

      ba0005p489
  • Steroid hormones and receptors
  • • Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment

      ba0005p490
    • Exposure to chronic stress induces bone loss via glucocorticoid signalling in osteoblasts

      ba0005p491
    • Distinct glucocorticoid receptor functions during inflammation and osteoporosis

      ba0005p492
• Late Breaking Abstracts
• • (1)
  • • All-trans retinoic acid can antagonize osteoblastogenesis induced by different BMPs irrespective of their dimerization types and dose- efficiencies

      ba0005lb1
    • Rat femoral neck research: an alternative method of histological sections

      ba0005lb2
    • Peripheral quantitative computed tomography measures contribute to the understanding of bone fragility in low-trauma fracture patients

      ba0005lb3
    • Bone mineral density in anorexia nervosa patients

      ba0005lb4
    • Posterior migration of fusion cages in degenerative lumbar disease treated with anterior lumbar interbody fusion

      ba0005lb5
    • Sclerostin blockade and zoledronic acid improve bone mass and strength in mice with exogenous hyperthyroidism

      ba0005lb6
    • Dose bisphosphonate-based anti-osteoporosis medication affect osteoporotic spinal fracture healing?

      ba0005lb7
    • Bone texture modifications during bone regeneration and osteocyte cell-signaling changes in response to treatment with Teriparatide

      ba0005lb8
    • First X-linked form of osteogenesis imperfecta, caused by mutations in MBTPS2, demonstrates a fundamental role for regulated intramembrane proteolysis in normal bone formation

      ba0005lb9
    • Abstract unavailable

      ba0005lb10
    • 25(OH)D₃ half-life is not influenced by vitamin D supplementation dose

      ba0005lb11
    • The role of Creld2 in skeletal development and homeostasis

      ba0005lb12
    • High-fat diet can accelerate the bone loss process of ovariectomized rats?

      ba0005lb13
    • Mechanical properties of rat tibia bone defect after treatment with latex membrane

      ba0005lb14
    • siRNA-mediated Noggin inhibition enhances osteogenesis and mineralization

      ba0005lb15
    • Proposal for a full-body suspension model for osteopenia induction

      ba0005lb16
    • Efficacy of the therapeutic compliance in the brittle bone disease and in the elderly people frailty

      ba0005lb17
    • Evidence that CD146 positive bone marrow stromal cells in bone metastases have an inhibitory role in regulating tumor growth

      ba0005lb18