ECTS2014 Poster Presentations Osteoporosis: evaluation and imaging (43 abstracts)
1D.F. Chebotarev Institute of Gerontology NAMS Ukraine, Kyiv, Ukraine; 2Center of Bone diseases, Lausanne University Hospital, Lausanne, Switzerland.
The aim of this study was to evaluate the trabecular bone score (TBS), bone mineral density (BMD) and body composition in men of various ages.
Materials and methods: 300 men aged 4087 years (mean age 60.5±0.6 years; mean height 1.61±0.003 m; mean weight 84.1±0.9 kg) were examined. The patients were divided into the following age-dependent groups: 4049 years (n=52), 5059 years (n=90), 6069 years (n=88), 7079 years (n=58), 8087 years (n=12). The BMD of total body, PA lumbar spine and proximal femur were measured by the DXA method (Prodigy, GEHC Lunar, Madison, WI, USA) and PA spine TBS were assessed by the TBS iNsight software package installed on our DXA machine (Med-Imaps, Pessac, France).
Results: We observed a significant decrease of TBS (L1L4) as a function of age (4049 years 1.161±0.022; 5059 years 1.108±0.018; 6069 years 1.114±0.016; 7079 years 1.061±0.024; 8087 years 1.105±0.049; F=2.49; P=0.04). We also found the decrease of BMD of lumbar spine (4049 years 1.186±0.003 g/cm2; 5059 years 1.128±0.021 g/cm2; 6069 years 1.224±0.026 g/cm2; 7079 years 1.247±0.034 g/cm2; 8087 years 1.131±0.064 g/cm2; F=3.25; P=0.01) and proximal femur (4049 years 1.050±0.021 g/cm2; 5059 years 0.996±0.018 g/cm2; 6069 years 1.032±0.018 g/cm2; 7079 years 1.004±0.021 g/cm2; 8087 years 0.879±0.050 g/cm2; F=3.34; P=0.01) with age.
Significant correlation was observed between TBS and BMD of lumbar spine (TBS=1.017+0.079×BMD (L1L4); r=0.11; t=1.90; P<0.05) and lean (TBS=1.441−0.000006×Lean mass (g); r=−0.25; t=−4.50; P=0.00001) and fat (TBS=1.33−0.000009×Fat mass (g); r=−0.54; t=−11.04; P<0.001) masses.
Conclusion: TBS and BMD in examined men significantly decreased with ageing. We have also found a significant correlation of TBS and BMD of lumbar spine, lean and fat masses.