ECTS2013 Poster Presentations Osteoporosis: pathophysiology and epidemiology (49 abstracts)
SE Lugansk State Medical University, Lugansk, Ukraine.
The purpose of this research was to study the histological structure of albino rats lower incisors of different ages after thymectomy under the injections of thymogen intrapritoneally.
Materials and methods: The experiment was conducted on 360 white rats of three age groups: immature, mature, and senile period.
Results: Injection of thymogen on the traditional pattern immature rats was accompanied by an increase in the width of the predentin layer, which is from 30 to 180 days was greater in the control 5.70, 7.48 and 7.43%. Also, at 90 and 180 days of the experiment and the width of the layer of odontoblasts mesio-distal incisor size were more control respectively by 4.77% and 5.14% and 3.37% and 3.88%. After the introduction thymogen adult rats on the traditional pattern layer predentin width was greater control with a 15 to 90 day experiment at 5.01, 5.57 and 4.50%. The width of the layer of odontoblasts was more control from 30 to 180 days at 4.67, 4.45 and 3.59%, and the mesio-distal size incisor to the 180 day 2.83%. Finally, i.p. injection thymogen old age rats was associated with significant differences from the control group with 90 days of the experiment. The width of the layer of odontoblasts and predentin, and mesial to distal incisor size, were more control values, respectively 5.75% and 5.46%, and 5.69% and 5.70% and 3.22% and 4.30%.
Conclusion: Injections of thymogen animals after thymectomy contribute to the development of compensatory changes in the tissues of the tooth and reduce the manifestation of osteoporosis.