ECTS2013 Poster Presentations Arthritis and other joint diseases: translational and clinical (18 abstracts)
Bone mineral density changes after total knee replacement in women over the age of 65
Deog Yoon Kim 1,
1Cheil General Hospital and Women’s Healthcare Center, Seoul, Republic of Korea; 2Ajou University School of Medicine, Suwon, Republic of Korea; 3Kyung Hee University Hospital, Seoul, Republic of Korea.
Objective: We analyze changes of spine BMD and hip BMD after total knee replacement (TKR) according to osteoporosis medication, bilaterality of operation site, degree of obesity, degree of knee function and osteoporosis diagnosis at operation in female patients above 65 years old, who received TKR due to severe knee osteoarthritis,
Method: 52 patients who checked 1 year follow-up BMD were enrolled. Patients were checked the spine and hip BMD at pre-operation and 1 year after operation. We reviewed bilaterality of operation site, degree of obesity, degree of knee function, osteoporosis diagnosis at operation and osteoporosis medication after operation (Table 1).
Result: Bilaterality of operation site, degree of obesity, degree of knee function, and osteoporosis diagnosis at operation don’t affect on BMD differences at 1 year after TKR. Calcium intake group increased spine BMD and decreased hip BMD. But bisphosphonate medication group increased spine BMD and hip BMD both. In bisphosphonate medication group, total hip BMD is significantly increased than calcium intake group (Table 2).
| Operation site | Unilateral 24 (46.2%) | Bilateral 28 (53.8%) |
| BMI | Normal 11 (21.2%) | Obesity 41 (78.8%) |
| Medication | Normal 11 (21.2%) | Bisphosphonate 38 (73.1%) |
| Diagnosis of osteoporosis | Osteopenia 32 (61.5%) | Osteoporosis 20 (38.5%) |
| Calcium group (14) | Bisphosphonate group (38) | P value | |
| Changes of BMD | |||
| Spine | 0.034 | 0.037 | 0.94 |
| Femur neck | −0.118 | 0.06 | 0.06 |
| Total hip | −0.020 | 0.017 | 0.01 |
| *P<0.05. | |||
Conclusion: Bisphosphonate medication for 1 year after TKR. prevents early reduction of hip BMD, regardless of osteoporosis diagnosis at operation.
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