Bone Abstracts

Introduction: The purpose of this research was to study the histological structure of albino rats lower incisors of different ages after thymectomy.

Materials and methods: The experiment was conducted on 360 white rats of three age groups: immature, mature and senile period. All animals were subjected to surgical thymectomy.

Results: In immature rats after thymectomy predentin layer width was less than the control from 30 till 180 days of the experiment, respectively 5.94, 4.69 and 6.89%. Also, on the 90 and 180 days experiment width dentin and mesial to distal incisor size was less control respectively by 4.67 and 4.62%, and 3.79 and 4.33%. After thymectomy in adult animals a similar picture observed, but expressed less width predentin layer was less than the control at 90 and 180 days after surgery to 5.72 and 6.49%, and on day 180 – the width of the layer of odontoblasts and the mineralized dentin, and also mesiodistal incisor size – 3.99, 4.75 and 3.11%.

In rats, old age width layers of odontoblasts and predentin and mesio-distal mandibular incisor size 90 and 180 days of the experiment were less control values, respectively, 4.15 and 4.65%, and 4.53 and 4.13%, and 2.62 and 2.93%. On day 180, and the width of the mineralized dentin layer was less than the control group – 5.74%.

Conclusion: Thymectomy has negative effects in the structure of the tooth, especially in immature animals.