Bone Abstracts

Traumatic injuries of the bones of various etiologies are accompanied not only a violation of their integrity, but also the development of a system osteopenic syndrome, which causes disorder neurohumoral regulation of the organism and has a negative effect on the structural and functional state of the skeletal tissues of other parts of the skeleton. The information concerning the characteristics of changes in the parameters of growth of molars of the mandible in the literature there are practically absent and contradictory. In the experiment, 84 adult male rats on days 7, 15, 30, 60, 90 and 180 day attempts to justify the possibility to offset the negative manifestations of the «fracture syndrome» on the growth parameters of molars of the mandible by implantation in the proximal tibial shaft biogenic hydroxyapatite. With the caliper was determined the length and height of the molar row of the mandible. The results were compared with the same parameters with the application of a defect in the same area of the tibia. After statistical analysis of data in the program «STATISTICA 5.5» found, that the length of the molar row was increased by 30 and 90 day observation at 3.23, 2.36%, and its height – only 90 days at 5.03% (P<0.05). Thus, we can assume that the implantation of biogenic hydroxyapatite accompanied smoothing inhibitory effect of application of the defect in the tibia on the growth processes of the molar row of the mandible in the later period of observation, presumably due to resorption of the implanted material and the release of calcium, phosphorus, boron and silicon, accelerating adaptation in tissues molars.