Pre-Clinical

see PP245....

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ba0001op22 | Pre-Clinical | ECTS2013

The effect of mTORC1 on postnatal skeletal development

Matthews Mary , Zannettino Andrew , Fitter Stephen , Martin Sally

see PP59....

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ba0001op23 | Pre-Clinical | ECTS2013

MEK inhibitors in fracture healing and NF1 pseudarthrosis

Little David , El-Hoss Jad , Kollind Mille , Deo Nikita , McDonald Michelle , Sullivan Kate , Little Chris , Schindeler Aaron

see PP60....

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ba0001op24 | Pre-Clinical | ECTS2013

Identification and characterization of a mesenchymal progenitor cell population involved in fracture healing

Matthews Brya , Grcevic Danka , Wang Liping , Hagiwara Yusuke , Adams Douglas , Kalajzic Ivo

see PP98....

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ba0001op25 | Pre-Clinical | ECTS2013

Oxygen tension-mediated regulation of chondrogenic differentiation: application to stem cells based osteochondral repair

Portron Sophie , Hivernaud Vincent , Merceron Christophe , Lesoeur Julie , Masson Martial , Gauthier Olivier , Vinatier Claire , Beck Laurent , Guicheux Jerome

see PP254....

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ba0001op26 | Pre-Clinical | ECTS2013

Bone is the main target of activation of Canonical Wnt pathway in osteoarthritis

Funck-Brentano Thomas , Bouaziz Wafa , Geoffroy Valerie , Hannouche Didier , Marty Caroline , Hay Eric , Cohen-Solal Martine

see PP17....

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ba0001op27 | Pre-Clinical | ECTS2013

Milk fat globule-epidermal growth factor 8 is a critical determinant of bone mass and alters the course of inflammation in arthritis

Sinningen Kathrin , Thiele Sylvia , Grossklaus Sylvia , Udey Mark , Hofbauer Lorenz C , Chavakis Triantafyllos , Rauner Martina

see PP18....

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ba0001op28 | Pre-Clinical | ECTS2013

Functional assessment of Paget's disease-causing mutations in sequestosome-1 (SQSTM1)

Azzam Eman , Helfrich Miep , Hocking Lynne

see PP493....

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ba0001op29 | Pre-Clinical | ECTS2013

miR-192 impairs invasion and tumor-induced osteolysis by repressing CCL2 in bone metastatic colonization

Valencia Karmele , Luis-Ravelo Diego , Bovy Nicolas , Martinez-Canarias Susana , Ormazabal Cristina , Zandueta Carolina , Anton Iker , Struman Ingrid , Tabruyn Sebastien , Segura Victor , De Las Rivas Javier , Bandres Eva

see PP154....

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ba0001op30 | Pre-Clinical | ECTS2013

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma

Lamoureux Francois , Baud'huin Marc , Ory Benjamin , Gleave Martin , Heymann Dominique , Redini Francoise

see PP137....

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ba0001op31 | Pre-Clinical | ECTS2013

Adipogenesis occurs at the expense of osteoblast differentiation in primary osteoblasts deficient in protease-activated receptor 2

Kularathna Pamuditha , Pagel Charles N , Hooper John D , Mackie Eleanor J

see PP167....

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ba0001op32 | Pre-Clinical | ECTS2013

Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity

Bartelt Alexander , Beil F Timo , Muller Brigitte , Kohne Till , Heine Markus , Yilmaz Tayfun , Heeren Joerg , Schinke Thorsten , Niemeier Andreas

see PP163....

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ba0001op33 | Pre-Clinical | ECTS2013

Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue

Deschaseaux Frederic , Gaillard Julien , Langonne Alain , Chauveau Christophe , Naji Abderrahim , Bouacida Amina , Rosset Philippe , Heymann Dominique , de Pinieux Gonzague , Rouas-Freiss Nathalie , Sensebe Luc

see PP178....

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ba0001op34 | Pre-Clinical | ECTS2013

Activation of the parathyroid hormone-receptor is involved in the pro-survival effect of hypotonic shock in osteocyte-like MLO-Y4 Cells

Maycas Marta , Ardura Juan A , de Castro Luis Fernandez , Gortazar Arancha , Esbrit Pedro

see PP242....

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ba0001op35 | Pre-Clinical | ECTS2013

Effects of a mutated sclerostin peptide on bone and lean mass in mice

Gerbaix Maude , Pierroz Dominique , Bonnet Nicolas , Boschert Verena , Mueller Thomas , Ferrari Serge

see PP432....

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ba0001op36 | Pre-Clinical | ECTS2013

N-cadherin governs age-related osteoprogenitor cell determination in mice through modulation of Wnt5a and Wnt10b

Hay Eric , Dieudonne Francois-Xavier , Marty Caroline , Marie Pierre J

see PP180....

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ba0001op37 | Pre-Clinical | ECTS2013

The D477N mutation in OPTN leads to increased bone turnover and enhanced osteoclast formation in Optn^D477N/D477N mice

Wani Sachin , Obaid Rami , Jones Ruth , Cohen Philip , Ralston Stuart , Albagha Omar

see PP229....

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ba0001op38 | Pre-Clinical | ECTS2013

BMP-9 induces the calcification of vascular smooth muscle cells

Zhu Dongxing , Mackenzie Neil , Farquharson Colin , MacRae Vicky

see PP494....

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ba0001op39 | Pre-Clinical | ECTS2013

Thrombin receptor deficiency leads to osteopetrosis by decreasing the RANKL/OPG ratio

van der Eerden BCJ , Tudpor K , Jongwattapapisan P , Woudenberg-Vrenken TE , Bindels RJM , Hoenderop JGJ , van Leeuwen JPTM

see PP205....

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ba0001op40 | Pre-Clinical | ECTS2013

Insertion of the clcn7 gene mutation pG213R in mouse induces autosomal dominant osteopetrosis type II

Fattore Andrea Del , Gray Amie K , Ichikawa Shoji , Chu Kang , Mohammad Khalid S , Capannolo Marta , Muraca Maurizio , Teti Anna , Econs Michael J , Alam Imranul

see PP474....

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Bone Abstracts

European Calcified Tissue Society Congress 2013

Oral Posters

IGF1 regulates MC-3T3 and human primary osteoblast to osteocyte differentiation in 3D culture

The effect of mTORC1 on postnatal skeletal development

MEK inhibitors in fracture healing and NF1 pseudarthrosis

Identification and characterization of a mesenchymal progenitor cell population involved in fracture healing

Oxygen tension-mediated regulation of chondrogenic differentiation: application to stem cells based osteochondral repair

Bone is the main target of activation of Canonical Wnt pathway in osteoarthritis

Milk fat globule-epidermal growth factor 8 is a critical determinant of bone mass and alters the course of inflammation in arthritis

Functional assessment of Paget's disease-causing mutations in sequestosome-1 (SQSTM1)

miR-192 impairs invasion and tumor-induced osteolysis by repressing CCL2 in bone metastatic colonization

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma

Adipogenesis occurs at the expense of osteoblast differentiation in primary osteoblasts deficient in protease-activated receptor 2

Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity

Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue

Activation of the parathyroid hormone-receptor is involved in the pro-survival effect of hypotonic shock in osteocyte-like MLO-Y4 Cells

Effects of a mutated sclerostin peptide on bone and lean mass in mice

N-cadherin governs age-related osteoprogenitor cell determination in mice through modulation of Wnt5a and Wnt10b

The D477N mutation in OPTN leads to increased bone turnover and enhanced osteoclast formation in Optn^D477N/D477N mice

BMP-9 induces the calcification of vascular smooth muscle cells

Thrombin receptor deficiency leads to osteopetrosis by decreasing the RANKL/OPG ratio

Insertion of the clcn7 gene mutation pG213R in mouse induces autosomal dominant osteopetrosis type II

BiosciAbstracts